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LRRTM2 controls presynapse nano-organization and AMPA receptor sub-positioning through Neurexin-binding interface

Synapse nanocolumns control neural transmission through precise alignment of neurotransmitter receptors and release sites. Here, the authors identify the Neurexin-LRRTM2 complex as a central organiser of excitatory synapse nanostructure and function.

Konstantina Liouta
Malgorzata Lubas
Ingrid Chamma
ResearchOpen Access11 Oct 2024
Nature Communications

Volume: 15, P: 1-18

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LRRTM2 controls presynapse nano-organization and AMPA receptor sub-positioning through Neurexin-binding interface

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