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Showing 151–200 of 203 results

Advanced filters: Author: Caroline Stack Clear advanced filters

Mutation identification by direct comparison of whole-genome sequencing data from mutant and wild-type individuals using k-mers

Genes that cause a mutant phenotype are efficiently identified from genetic screens of model and non-model organisms from whole-genome sequencing data without requiring segregating populations, genetic maps and reference sequences.

Karl J V Nordström
Maria C Albani
Korbinian Schneeberger
Research10 Mar 2013
Nature Biotechnology

Volume: 31, P: 325-330
Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis

A complex interplay involving Notch- and Erbb2-mediated signalling between cardiomyocytes guides the morphogenesis of the ventricular wall.

Peidong Han
Joshua Bloomekatz
Neil C. Chi
Research29 Jun 2016
Nature

Volume: 534, P: 700-704
A three-dimensional human neural cell culture model of Alzheimer’s disease

Early-onset familial Alzheimer’s disease mutations induce both amyloid-β and tau pathologies in differentiated human neural stem cells in 3D cultures.

Se Hoon Choi
Young Hye Kim
Doo Yeon Kim
Research12 Oct 2014
Nature

Volume: 515, P: 274-278
Recurrent network activity drives striatal synaptogenesis

Neurotransmitter release and activity are modulated in the striatum of mice to demonstrate that the balance of activity within the two antagonistic, inhibitory pathways co-mingled in this nucleus regulates excitatory innervation of the basal ganglia during development.

Yevgenia Kozorovitskiy
Arpiar Saunders
Bernardo L. Sabatini
Research13 May 2012
Nature

Volume: 485, P: 646-650
Physiological correlates of cognitive load in laparoscopic surgery

Zohreh Zakeri
Neil Mansfield
Ahmet Omurtag
ResearchOpen Access31 Jul 2020
Scientific Reports

Volume: 10, P: 1-13
In vivo detection of programmed cell death during mouse heart development

Kristel Martínez-Lagunas
Yoshifumi Yamaguchi
Michael Hesse
ResearchOpen Access30 Sept 2019
Cell Death & Differentiation

Volume: 27, P: 1398-1414
A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

Claudio Raimondi
Veronique Calleja
Marco Falasca
ResearchOpen Access20 May 2016
Scientific Reports

Volume: 6, P: 1-14
A high-throughput multispectral imaging system for museum specimens

An accessible approach to multispectral imaging analysis of museum butterfly specimens is presented using consumer technology.

Wei-Ping Chan
Richard Rabideau Childers
Naomi E. Pierce
ResearchOpen Access01 Dec 2022
Communications Biology

Volume: 5, P: 1-13
Distinct molecular profiles and shared drug vulnerabilities in pancreatic metastases of renal cell carcinoma

Functional precision medicine approach reveals genomic and transcriptomic aberrations that distinguish pancreatic metastases from other types of ccRCC metastases and suggest potential therapeutic targets at the individual level.

Matilda Roos-Mattila
Pauliina Kallio
Hanna E. Seppänen
ResearchOpen Access20 Oct 2024
Communications Biology

Volume: 7, P: 1-18
The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation

Maxence Nachury, Christel Thauvin-Robinet and colleagues identify mutations in C2CD3 in two families with oral-facial-digital syndrome. They further show that C2CD3 localizes to the distal end of centrioles and acts as a positive regulator of centriole elongation.

Christel Thauvin-Robinet
Jaclyn S Lee
Maxence V Nachury
Research06 Jul 2014
Nature Genetics

Volume: 46, P: 905-911
Perspectives on obesity imaging: [¹⁸F]2FNQ1P a specific 5-HT₆ brain PET radiotracer

Pierre Courault
Sandrine Bouvard
Sophie Lancelot
ResearchOpen Access07 Oct 2024
International Journal of Obesity

Volume: 49, P: 133-139
Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy

Corinne A. Betts
Amer F. Saleh
Matthew J. A. Wood
ResearchOpen Access26 Jun 2015
Scientific Reports

Volume: 5, P: 1-13
A human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor–RPE interface

CLN3 disease is characterised by childhood-onset vision loss and premature death. Using patient-derived retinal cells, the authors show that CLN3 is required for retinal pigment epithelium (RPE) cell structure, microvilli and phagocytosis of photoreceptor outer segments that are essential for vision. They further suggest that gene-therapy targeting RPE cells can be effective for CLN3 disease.

Cynthia Tang
Jimin Han
Ruchira Singh
ResearchOpen Access05 Feb 2021
Communications Biology

Volume: 4, P: 1-18
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

The analysis of T-cell antigens in long-term survivors of pancreatic ductal adenocarcinoma suggests that neoantigen immunogenicity and quality, not purely quantity, correlate with survival.

Vinod P. Balachandran
Marta Łuksza
Steven D. Leach
Research01 Nov 2017
Nature

Volume: 551, P: 512-516
Characterization and Validation of a Human 3D Cardiac Microtissue for the Assessment of Changes in Cardiac Pathology

Caroline R. Archer
Rebecca Sargeant
Amy Pointon
ResearchOpen Access05 Jul 2018
Scientific Reports

Volume: 8, P: 1-15
The relationship between oxidant levels and gut physiology in a litter-feeding termite

Gessica Sousa
Ana Caroline P. Gandara
Ednildo A. Machado
ResearchOpen Access24 Jan 2019
Scientific Reports

Volume: 9, P: 1-9
An in vitro platform for quantifying cell cycle phase lengths in primary human intestinal epithelial cells

Michael J. Cotton
Pablo Ariel
Joseph Burclaff
ResearchOpen Access02 Jul 2024
Scientific Reports

Volume: 14, P: 1-16
Detection of inflammatory cell function using ¹³C magnetic resonance spectroscopy of hyperpolarized [6-¹³C]-arginine

Chloé Najac
Myriam M. Chaumeil
Sabrina M. Ronen
ResearchOpen Access10 Aug 2016
Scientific Reports

Volume: 6, P: 1-10
MRI Assessment of Cardiomyopathy Induced by β1-Adrenoreceptor Autoantibodies and Protection Through β3-Adrenoreceptor Overexpression

Laetitia Vanhoutte
Céline Guilbaud
Olivier Feron
ResearchOpen Access09 Mar 2017
Scientific Reports

Volume: 7, P: 1-10
Gingival proteomics reveals the role of TGF beta and YAP/TAZ signaling in Raine syndrome fibrosis

Cláudio Rodrigues Rezende Costa
Rym Chalgoumi
Ana Carolina Acevedo
ResearchOpen Access25 Apr 2024
Scientific Reports

Volume: 14, P: 1-24
Label-free functional analysis of root-associated microbes with dynamic quantitative oblique back-illumination microscopy

Caroline E. Serafini
Madison Green
Francisco E. Robles
ResearchOpen Access09 Mar 2024
Scientific Reports

Volume: 14, P: 1-13
Beta-nerve growth factor stimulates spontaneous electrical activity of in vitro embryonic mouse GnRH neurons through a P75 mediated-mechanism

Caroline Pinet-Charvet
Renaud Fleurot
Anne H Duittoz
ResearchOpen Access30 Jun 2020
Scientific Reports

Volume: 10, P: 1-14
Intracellular amorphous Ca-carbonate and magnetite biomineralization by a magnetotactic bacterium affiliated to the Alphaproteobacteria

Caroline L. Monteil
Karim Benzerara
Christopher T. Lefevre
Research24 Aug 2020
The ISME Journal

Volume: 15, P: 1-18
Mapping brucellosis risk in Kenya and its implications for control strategies in sub-Saharan Africa

James M. Akoko
Athman Mwatondo
Bernard Bett
ResearchOpen Access18 Nov 2023
Scientific Reports

Volume: 13, P: 1-11
Development and qualification of clinical grade decellularized and cryopreserved human esophagi

William Godefroy
Lionel Faivre
Lousineh Arakelian
ResearchOpen Access25 Oct 2023
Scientific Reports

Volume: 13, P: 1-17
PTEN-restoration abrogates brain colonisation and perivascular niche invasion by melanoma cells

Sarah Wang
Caroline P. Riedstra
Andrew C. Dudley
Research26 Dec 2023
British Journal of Cancer

Volume: 130, P: 555-567
Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-γ-induced microglial activation

Bolanle Fatimat Olabiyi
Anne-Caroline Schmoele
Andreas Zimmer
ResearchOpen Access10 Jul 2023
Scientific Reports

Volume: 13, P: 1-11
Exploring the private universe of Henri Matisse in The Red Studio

Abed Haddad
Gianluca Pastorelli
Lynda Zycherman
ResearchOpen Access23 Oct 2022
Heritage Science

Volume: 10, P: 1-25
Endotracheal tube biofilm in critically ill patients during the COVID-19 pandemic : description of an underestimated microbiological compartment

Thomas Maldiney
Valentin Pineau
Jean-Pierre Quenot
ResearchOpen Access27 Dec 2022
Scientific Reports

Volume: 12, P: 1-13
Lateral confined growth of cells activates Lef1 dependent pathways to regulate cell-state transitions

Luezhen Yuan
Bibhas Roy
G. V. Shivashankar
ResearchOpen Access15 Oct 2022
Scientific Reports

Volume: 12, P: 1-13
Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development

Natalie Page
Mark Wappett
Timothy Harrison
ResearchOpen Access20 Sept 2022
Scientific Reports

Volume: 12, P: 1-14
Rearrangements in the musculature correlate with jumping behaviour in legless Mediterranean fruit fly larvae Ceratitis capitata (Tephritidae)

Max Diesner
Marcel Brenner
Hermann Aberle
ResearchOpen Access06 May 2022
Scientific Reports

Volume: 12, P: 1-11
Zernike phase-contrast electron cryotomography applied to marine cyanobacteria infected with cyanophages

Equipping an electron microscope with Zernike phase-contrast optics dramatically increases the contrast of the images. Dai et al. describe how to successfully apply this technology for the acquisition and analysis of electron tomograms.

Wei Dai
Caroline Fu
Wah Chiu
Protocols16 Oct 2014
Nature Protocols

Volume: 9, P: 2630-2642
Standardized production of hPSC-derived cardiomyocyte aggregates in stirred spinner flasks

We present a protocol for achieving efficient generation of hPSC-CM aggregates in suspension culture, emphasizing process simplicity, robustness and GMP compliance. The strategy promotes clinical translation and other applications that require large numbers of CMs.

Nils Kriedemann
Wiebke Triebert
Robert Zweigerdt
Protocols28 Mar 2024
Nature Protocols

Volume: 19, P: 1911-1939
Carboxyl-richness controls organic carbon preservation during coprecipitation with iron (oxyhydr)oxides in the natural environment

Organic carbon sequestration, stabilisation and burial through its interaction with iron is enhanced by carboxyl-richness of the organic moiety, according to elemental and microstructure analysis of experimentally produced co-precipitates.

Lisa Curti
Oliver W. Moore
Caroline L. Peacock
ResearchOpen Access04 Nov 2021
Communications Earth & Environment

Volume: 2, P: 1-13
Interobserver variability in the assessment of stromal tumor-infiltrating lymphocytes (sTILs) in triple-negative invasive breast carcinoma influences the association with pathological complete response: the IVITA study

Mieke R. Van Bockstal
Aline François
Christine Galant
Research03 Jul 2021
Modern Pathology

Volume: 34, P: 2130-2140
Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis

Maggie A. Khuu
Thara Nallamothu
Alfredo J. Garcia III
ResearchOpen Access16 Mar 2021
Scientific Reports

Volume: 11, P: 1-13
Visualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST

Yankel Chekli
Caroline Peron-Cane
Christophe Beloin
ResearchOpen Access25 Sept 2020
Scientific Reports

Volume: 10, P: 1-13
Interobserver variability in upfront dichotomous histopathological assessment of ductal carcinoma in situ of the breast: the DCISion study

Hélène Dano
Serdar Altinay
Mieke R. Van Bockstal
Research18 Sept 2019
Modern Pathology

Volume: 33, P: 354-366
Whole-Brain Vasculature Reconstruction at the Single Capillary Level

Antonino Paolo Di Giovanna
Alessandro Tibo
Francesco Saverio Pavone
ResearchOpen Access22 Aug 2018
Scientific Reports

Volume: 8, P: 1-11
The MUC5B mucin polymer is dominated by repeating structural motifs and its topology is regulated by calcium and pH

Gareth W. Hughes
Caroline Ridley
David J. Thornton
ResearchOpen Access22 Nov 2019
Scientific Reports

Volume: 9, P: 1-13
Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration

Jian-Nan Zhang
Uwe Michel
Jan C. Koch
ResearchOpen Access15 Nov 2016
Scientific Reports

Volume: 6, P: 1-15
Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice

Corinne A. Betts
Amer F. Saleh
Matthew J. A. Wood
ResearchOpen Access11 Mar 2015
Scientific Reports

Volume: 5, P: 1-9
The development of novel LTA₄H modulators to selectively target LTB₄ generation

Caroline M. Low
Samia Akthar
Robert J. Snelgrove
ResearchOpen Access17 Mar 2017
Scientific Reports

Volume: 7, P: 1-13
Human snoRNA-93 is processed into a microRNA-like RNA that promotes breast cancer cell invasion

Dillon G. Patterson
Justin T. Roberts
Glen M. Borchert
ResearchOpen Access10 Jul 2017
npj Breast Cancer

Volume: 3, P: 1-12
Stromal striae: a new insight into corneal physiology and mechanics

Kate Grieve
Djida Ghoubay
Vincent Borderie
ResearchOpen Access19 Oct 2017
Scientific Reports

Volume: 7, P: 1-11
Live imaging of axonal transport in Drosophila pupal brain explants

This protocol describes live imaging of axonal transport in Drosophila pupal brains. It complements previous techniques for imaging larval neurons by enabling the study of extensive changes occurring during metamorphosis.

Caroline Medioni
Anne Ephrussi
Florence Besse
Protocols12 Mar 2015
Nature Protocols

Volume: 10, P: 574-584
A modular approach to the design, fabrication, and characterization of muscle-powered biological machines

This protocol describes steps to design and generate biological machines. Ring-shaped skeletal muscle actuators are cultured and coupled to a 3D-printed skeleton. Contraction of muscle rings can be controlled by optical or electrical stimulation.

Ritu Raman
Caroline Cvetkovic
Rashid Bashir
Protocols09 Feb 2017
Nature Protocols

Volume: 12, P: 519-533
Assessing the contribution of diazotrophs to microbial Fe uptake using a group specific approach in the Western Tropical South Pacific Ocean

C. Lory
F. Van Wambeke
S. Bonnet
ResearchOpen Access27 Apr 2022
ISME Communications

Volume: 2, P: 1-11
Regional-scale management maps for forested areas of the Southeastern United States and the US Pacific Northwest

Matthew Marsik
Caroline G. Staub
Michael W. Binford
ResearchOpen Access28 Aug 2018
Scientific Data

Volume: 5, P: 1-13

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