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Signal Transduction and Targeted Therapy (2)
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In vivo protein interaction network analysis reveals porin-localized antibiotic inactivation in Acinetobacter baumannii strain AB5075

The bacterial pathogen Acinetobacter baumannii has evolved resistance to many antibiotics, including carbapenems. Here, Wu et al. show that the carbapenemase Oxa-23 interacts with the outer membrane porin CarO in an A. baumanniiisolate, indicative of porin-localised antibiotic inactivation.

Xia Wu
Juan D. Chavez
James E. Bruce
ResearchOpen Access11 Nov 2016
Nature Communications

Volume: 7, P: 1-14
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

Qi Zhang
Bridget Riley-Gillis
Marina Konopleva
ResearchOpen Access21 Feb 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-13
Correction: Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

Qi Zhang
Bridget Riley-Gillis
Marina Konopleva
Amendments and CorrectionsOpen Access01 Apr 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1

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