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Showing 1–3 of 3 results
Advanced filters: Author: Catherine Regnard Clear advanced filters

  • Lassa virus vaccination is impeded by the limited capacity of vaccine candidates to induce rapid protection. In this study, the authors found that a single shot of a measles-based Lassa vaccine protected nonhuman primates 16 or 8 days after vaccination.

    • Mathieu Mateo
    • Stéphanie Reynard
    • Sylvain Baize
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • The chromosomal kinase JIL-1 is responsible for interphase histone H3S10 phosphorylation and has been proposed to protect active chromatin from heterochromatinisation. Here, the authors show that JIL-1 is stabilized and anchored to active genes and telomeric transposons by JASPer, which binds to H3K36me3 nucleosomes via its PWWP domain.

    • Christian Albig
    • Chao Wang
    • Catherine Regnard
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-17

  • PWWP2A is a chromatin-binding transcriptional regulator that mediates mitosis-progression. Here, the authors provide evidence that PWWP2A directly interacts with H2A.Z nucleosomes, DNA and H3K36me3, binds to an MTA1-specific subcomplex of the NuRD complex (M1HR) and promotes changes to histone acetylation.

    • Stephanie Link
    • Ramona M. M. Spitzer
    • Sandra B. Hake
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16