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Showing 1–3 of 3 results
Advanced filters: Author: Cathleen Holze Clear advanced filters

  • Whether there are conserved nucleic acid (NA) binding proteins across species is not fully known. Using data from human, mouse and fly, the authors identify common binders, implicate TAOKs and show that these kinases bind NAs across species and promote virus defence in mammalian cells.

    • Friederike L. Pennemann
    • Assel Mussabekova
    • Andreas Pichlmair
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-22

  • Reactive oxygen species (ROS) are generated by cells during viral infection. Pichlmair and colleagues demonstrate a ROS-dependent form of cell death, ‘oxeiptosis’, that resembles apoptosis but uses a pathway distinct from all previously described death pathways.

    • Cathleen Holze
    • Chloé Michaudel
    • Andreas Pichlmair
    Research
    Nature Immunology
    Volume: 19, P: 130-140