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Showing 1–3 of 3 results

Advanced filters: Author: Chaima Benaksas Clear advanced filters

P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia

Wood and colleagues report that the XPO1 inhibitor selinexor activates PI3Ky-dependent AKT signaling in AML via upregulation of P2RY2 and demonstrate a synergistic effect of combining selinexor with inhibition of prosurvival AKT signaling.

Kevin H. Lin
Justine C. Rutter
Kris C. Wood
Research06 Jun 2022
Nature Cancer

Volume: 3, P: 837-851
A multiparametric niche-like drug screening platform in acute myeloid leukemia

Reinaldo Dal Bello
Justine Pasanisi
Raphael Itzykson
ResearchOpen Access24 Jun 2022
Blood Cancer Journal

Volume: 12, P: 1-12
Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia

Bryann Pardieu
Justine Pasanisi
Raphael Itzykson
Research26 Apr 2022
Leukemia

Volume: 36, P: 1585-1595