Nature Search

A biodegradable, flexible photonic patch for in vivo phototherapy

Illuminating internal organs and tissues with high controllability and adaptability remains challenging. Here the authors present a flexible, biodegradable photonic device called iCarP for large area, high intensity, wide spectrum, deeply penetrating, continuous or pulsatile illumination.

Kaicheng Deng
Yao Tang
Yang Zhu
ResearchOpen Access27 May 2023
Nature Communications

Volume: 14, P: 1-15
Shape-recovery of implanted shape-memory devices remotely triggered via image-guided ultrasound heating

Focused ultrasound could be used to change the geometry of implanted shape-memory medical devices noninvasively. Here, the authors demonstrate this concept on large animal models, showing device removal and trigger drug release.

Yang Zhu
Kaicheng Deng
William R. Wagner
ResearchOpen Access06 Feb 2024
Nature Communications

Volume: 15, P: 1-12
Epicardial transplantation of antioxidant polyurethane scaffold based human amniotic epithelial stem cell patch for myocardial infarction treatment

Myocardial infarction is a leading cause of death globally. Stem cell therapy is considered a potential treatment. Here, the authors propose an antioxidant polyurethane-based cardiac patch with stem cells that provides antioxidation, immune remodeling and paracrine modulation for myocardial repair.

Jinying Li
Yuejun Yao
Luyang Yu
ResearchOpen Access22 Oct 2024
Nature Communications

Volume: 15, P: 1-16
Polyrotaxane-based supramolecular theranostics

Multifunctional nanomedicine platforms are highly promising for anticancer therapy. Here, the authors design polyrotaxane-based theranostic nanoparticles that combine targeted drug delivery with photothermal behaviour to exhibit potent anti-tumour effects in vivo.

Guocan Yu
Zhen Yang
Xiaoyuan Chen
ResearchOpen Access22 Feb 2018
Nature Communications

Volume: 9, P: 1-13
A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy

It is challenging to design photosensitizers (PS) with high quantum yields generating singlet oxygen due to severe aggregation between the hydrophobic PSs. Here they develop organoplatinum(II) metallatocage-based PS to overcome these challenges and show excellent antitumor effect.

Guocan Yu
Shan Yu
Xiaoyuan Chen
ResearchOpen Access18 Oct 2018
Nature Communications

Volume: 9, P: 1-18
Paternal heroin self-administration in rats increases drug-seeking behavior in male offspring via miR-19b downregulation in the nucleus accumbens

Wenjing Gao
Tingting Wang
Qiumin Le
ResearchOpen Access08 Mar 2025
Neuropsychopharmacology

Volume: 50, P: 1027-1038
Gene-activated matrix/bone marrow-derived mesenchymal stem cells constructs regenerate sweat glands-like structure in vivo

Pranish Kolakshyapati
Xiuyuan Li
Changyou Gao
ResearchOpen Access15 Dec 2017
Scientific Reports

Volume: 7, P: 1-13
Surface-anchored poly(acryloyl-L(D)-valine) with enhanced chirality-selective effect on cellular uptake of gold nanoparticles

Jun Deng
Sai Wu
Changyou Gao
ResearchOpen Access17 Aug 2016
Scientific Reports

Volume: 6, P: 1-12
In vivo vascularization of MSC-loaded porous hydroxyapatite constructs coated with VEGF-functionalized collagen/heparin multilayers

Kai Jin
Bo Li
Changyou Gao
ResearchOpen Access22 Jan 2016
Scientific Reports

Volume: 6, P: 1-13
Design of gene-activated matrix for the repair of skin and cartilage

Combining gene therapy and tissue engineering, gene-activated matrix (GAM) is able to activate cells in or near the scaffolds to express the desired growth factors at effective levels within the local tissue microenvironment and further to restore the structure and function of damaged or dysfunctional tissues like skin, cartilage, bone, vessel, muscle, tendon and so on.

Chunfen Wang
Lie Ma
Changyou Gao
Reviews25 Jun 2014
Polymer Journal

Volume: 46, P: 476-482

Search

A biodegradable, flexible photonic patch for in vivo phototherapy

Shape-recovery of implanted shape-memory devices remotely triggered via image-guided ultrasound heating

Epicardial transplantation of antioxidant polyurethane scaffold based human amniotic epithelial stem cell patch for myocardial infarction treatment

Polyrotaxane-based supramolecular theranostics

A discrete organoplatinum(II) metallacage as a multimodality theranostic platform for cancer photochemotherapy

Paternal heroin self-administration in rats increases drug-seeking behavior in male offspring via miR-19b downregulation in the nucleus accumbens

Gene-activated matrix/bone marrow-derived mesenchymal stem cells constructs regenerate sweat glands-like structure in vivo

Surface-anchored poly(acryloyl-L(D)-valine) with enhanced chirality-selective effect on cellular uptake of gold nanoparticles

In vivo vascularization of MSC-loaded porous hydroxyapatite constructs coated with VEGF-functionalized collagen/heparin multilayers

Design of gene-activated matrix for the repair of skin and cartilage

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