Epilepsy develops in many patients with glioma, and the two presentations are currently treated with independent therapies. In this Review, Huberfeld and Vecht provide an overview of the evidence that epilepsy and gliomas share pathogenic mechanisms that could be targeted to simultaneously manage seizures and target tumours. They consider the benefits and risks of using antiepileptic drugs to treat gliomas, and antitumour drugs to control epilepsy.
- Gilles Huberfeld
- Charles J. Vecht
