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Showing 1–2 of 2 results
Advanced filters: Author: Charlotta Ryk Clear advanced filters
  • Thorunn Rafnar and colleagues identify a variant on 4p16.3 near FGFR3 associated with increased risk of urinary bladder cancer. They find that the risk allele is more frequent among individuals with tumors that carry an activating somatic mutation in FGFR3, suggesting a link between germline variation, somatic mutation status and cancer risk.

    • Lambertus A Kiemeney
    • Patrick Sulem
    • Kari Stefansson
    Research
    Nature Genetics
    Volume: 42, P: 415-419
  • Kari Stefansson and colleagues report results of a genome-wide association study for urinary bladder cancer. The strongest association was with a variant on 8q24, located 30 kb upstream of MYC in a haplotype block distinct from previously reported 8q24 cancer risk variants.

    • Lambertus A Kiemeney
    • Steinunn Thorlacius
    • Kari Stefansson
    Research
    Nature Genetics
    Volume: 40, P: 1307-1312