Nature Search

Changes in neurotensin signalling drive hedonic devaluation in obesity

In mice, prolonged consumption of a high-fat diet decreases interest in calorie-rich foods as a result of reduced neurotensin expression and signalling, which uncouples hedonic feeding behaviour linked to neurons projecting from lateral nucleus accumbens to ventral tegmental area.

Neta Gazit Shimoni
Amanda J. Tose
Stephan Lammel
ResearchOpen Access26 Mar 2025
Nature

Volume: 641, P: 1238-1247
Author Correction: Surfaceome dynamics reveal proteostasis-independent reorganization of neuronal surface proteins during development and synaptic plasticity

Marc van Oostrum
Benjamin Campbell
Bernd Wollscheid
Amendments and CorrectionsOpen Access06 Nov 2020
Nature Communications

Volume: 11, P: 1
Copy number architectures define treatment-mediated selection of lethal prostate cancer clones

The heterogeneity of androgen receptor (AR) gene alterations across metastases in prostate cancer remains unresolved. Here, the authors characterise AR genomic complexity across spatially separated lethal metastases from 10 prostate cancer patients and investigate how AR alterations evolve.

A. M. Mahedi Hasan
Paolo Cremaschi
Gerhardt Attard
ResearchOpen Access10 Aug 2023
Nature Communications

Volume: 14, P: 1-16
Surfaceome dynamics reveal proteostasis-independent reorganization of neuronal surface proteins during development and synaptic plasticity

Cell surface proteins contribute to neuronal development and activity-dependent synaptic plasticity. Here, the authors perform a time-resolved surfaceome analysis of developing primary neurons and in response to homeostatic synaptic scaling and chemical long-term potentiation (cLTP), revealing surface proteome remodeling largely independent of global proteostasis.

Marc van Oostrum
Benjamin Campbell
Bernd Wollscheid
ResearchOpen Access05 Oct 2020
Nature Communications

Volume: 11, P: 1-16
Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

The spike protein of the Omicron variant of SARS-CoV-2 has a higher affinity for ACE2 than Delta, and a marked change in its antigenicity increases Omicron’s evasion of therapeutic and vaccine-elicited neutralizing antibodies.

Bo Meng
Adam Abdullahi
Ravindra K. Gupta
ResearchOpen Access01 Feb 2022
Nature

Volume: 603, P: 706-714
Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands

Jorge Reis-Filho and colleagues identify recurrent mutations in PRKD1 in 73% of polymorphous low-grade adenocarcinoma, a malignant tumor of the minor salivary glands. The mutations cause activation of the PRKD1 serine-threonine kinase.

Ilan Weinreb
Salvatore Piscuoglio
Jorge S Reis-Filho
Research21 Sept 2014
Nature Genetics

Volume: 46, P: 1166-1169
SARS-Cov-2 vaccination strategies in hospitalized recovered COVID-19 patients: a randomized clinical trial (VATICO Trial)

Sofía Sábato
Susana Benet
He Ping Yeo
ResearchOpen Access22 Mar 2025
Scientific Reports

Volume: 15, P: 1-16
Potential pitfalls in the use of real-world data for studying long COVID

Harrison G. Zhang
Jacqueline P. Honerlaw
Gabriel A. Brat
Correspondence13 Apr 2023
Nature Medicine

Volume: 29, P: 1040-1043
Prevalence and natural history of schwannomas in neurofibromatosis type 2 (NF2): the influence of pathogenic variants

Daniel Moualed
Jonathan Wong
Simon Freeman
Research24 Jan 2022
European Journal of Human Genetics

Volume: 30, P: 458-464
International comparisons of laboratory values from the 4CE collaborative to predict COVID-19 mortality

Griffin M. Weber
Chuan Hong
Gabriel A. Brat
ResearchOpen Access13 Jun 2022
npj Digital Medicine

Volume: 5, P: 1-8
Multinational characterization of neurological phenotypes in patients hospitalized with COVID-19

Trang T. Le
Alba Gutiérrez-Sacristán
Zongqi Xia
ResearchOpen Access12 Oct 2021
Scientific Reports

Volume: 11, P: 1-13
Data from a pre-publication independent replication initiative examining ten moral judgement effects

Warren Tierney
Martin Schweinsberg
Eric Luis Uhlmann
ResearchOpen Access11 Oct 2016
Scientific Data

Volume: 3, P: 1-7

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Changes in neurotensin signalling drive hedonic devaluation in obesity

Author Correction: Surfaceome dynamics reveal proteostasis-independent reorganization of neuronal surface proteins during development and synaptic plasticity

Copy number architectures define treatment-mediated selection of lethal prostate cancer clones

Surfaceome dynamics reveal proteostasis-independent reorganization of neuronal surface proteins during development and synaptic plasticity

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands

SARS-Cov-2 vaccination strategies in hospitalized recovered COVID-19 patients: a randomized clinical trial (VATICO Trial)

Potential pitfalls in the use of real-world data for studying long COVID

Prevalence and natural history of schwannomas in neurofibromatosis type 2 (NF2): the influence of pathogenic variants

International comparisons of laboratory values from the 4CE collaborative to predict COVID-19 mortality

Multinational characterization of neurological phenotypes in patients hospitalized with COVID-19

Data from a pre-publication independent replication initiative examining ten moral judgement effects

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