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Advanced filters: Author: Charuhas Deshpande Clear advanced filters
  • Loss of RB promotes both malignant progression and the development of metastatic disease; however, whereas reactivation of the RB pathway can revert metastatic tumour cell states to non-metastatic cell states, malignant cell proliferation is supported by MAPK–CDK2-dependent suppression of RB.

    • David M. Walter
    • Travis J. Yates
    • David M. Feldser
    Research
    Nature
    Volume: 569, P: 423-427