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Showing 1–3 of 3 results
Advanced filters: Author: Chee-Huat Linus Eng Clear advanced filters

  • Multiplexed imaging of 3,660 chromosomal loci in individual mouse embryonic stem cells by DNA seqFISH+ with immunofluorescence of 17 chromatin marks and subnuclear structures reveals invariant organization of loci within individual cells, and heterogeneous and long-lived distinct combinatorial chromatin states in cellular subpopulations.

    • Yodai Takei
    • Jina Yun
    • Long Cai
    Research
    Nature
    Volume: 590, P: 344-350

  • seqFISH+, an evolution of sequential fluorescence in situ hybridization with super-resolution imaging capabilities, is used to image mRNAs of 10,000 genes in cultured cells and mouse brain slices, demonstrating the ability to generate spatial atlases and to perform discovery-driven studies in situ.

    • Chee-Huat Linus Eng
    • Michael Lawson
    • Long Cai
    Research
    Nature
    Volume: 568, P: 235-239

  • RNA SPOTs adapts sequential fluorescence in situ hybridization (seqFISH) for highly accurate and inexpensive transcriptome-scale or targeted RNA quantification in vitro.

    • Chee-Huat Linus Eng
    • Sheel Shah
    • Long Cai
    Research
    Nature Methods
    Volume: 14, P: 1153-1155