Asymmetric C–H functionalisation provides efficient synthetic routes to chiral metallocenes; however, these methods are often limited by the substitution patterns that can be accessed. Now, a Rh-catalysed enantioselective C–H arylation provides access to chiral 1,2-disubstituted and 1,3-disubstituted metallocenes via kinetic resolution of pre-functionalised metallocenes.
- Chen-Xu Liu
- Fangnuo Zhao
- Shu-Li You
