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Signal Transduction and Targeted Therapy (1)
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Showing 1–3 of 3 results

Advanced filters: Author: Chenying Fu Clear advanced filters

Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia

Ten-eleven translocation 1 (TET1) is a critical oncoprotein in AML. Here, the authors identify 2 compounds that target the binding of STAT3/5 specifically to the TET1 promoter, inhibiting its expression and AML cell viability.

Xi Jiang
Chao Hu
Jianjun Chen
ResearchOpen Access13 Dec 2017
Nature Communications

Volume: 8, P: 1-13
ALOX5 exhibits anti-tumor and drug-sensitizing effects in MLL-rearranged leukemia

Yungui Wang
Jennifer R. Skibbe
Xi Jiang
ResearchOpen Access12 May 2017
Scientific Reports

Volume: 7, P: 1-11
Signaling pathways and targeted therapy for myocardial infarction

Qing Zhang
Lu Wang
Quan Wei
ReviewsOpen Access10 Mar 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-38