RNA modifications play critical roles in gene expression regulation, RNA stability, and translation efficiency, however, the detection of RNA modifications by various sequencing approaches may present differing results. Here, the authors explore several computational methods for the detection of the most researched mRNA modifications, with a view to improving algorithms’ comparability, reliability, and consistency in RNA modification prediction.
- Jannes Spangenberg
- Stefan Mündnich
- Nicolo Alagna
