Chen et al. apply a multi-level approach to show that serotonin signaling modulates neuronal responses to both threatening and non-threatening voices even in the pre-attentive stage. They show that 5-HTTLPR short-allele carriers had higher baseline event-related potentials and lower fearful mismatch negativity, which can be reversed by acute anxiolytic treatment.
- Chenyi Chen
- Róger M. Martínez
- Yawei Cheng