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Showing 1–5 of 5 results
Advanced filters: Author: Chris Heyes Clear advanced filters
  • Scientific research on consciousness is critical to multiple scientific, clinical, and ethical issues. The growth of the field could also be beneficial to several areas including neurology and mental health research. To achieve this goal, we need to set funding priorities carefully and address problems such as job creation and potential media misrepresentation.

    • Matthias Michel
    • Diane Beck
    • Masatoshi Yoshida
    Comments & Opinion
    Nature Human Behaviour
    Volume: 3, P: 104-107
  • Humans strive to design safe AI systems that align with our goals and remain under our control. However, as AI capabilities advance, we face a new challenge: the emergence of deeper, more persistent relationships between humans and AI systems. We explore how increasingly capable AI agents may generate the perception of deeper relationships with users, especially as AI becomes more personalised and agentic. This shift, from transactional interaction to ongoing sustained social engagement with AI, necessitates a new focus on socioaffective alignment—how an AI system behaves within the social and psychological ecosystem co-created with its user, where preferences and perceptions evolve through mutual influence. Addressing these dynamics involves resolving key intrapersonal dilemmas, including balancing immediate versus long-term well-being, protecting autonomy, and managing AI companionship alongside the desire to preserve human social bonds. By framing these challenges through a notion of basic psychological needs, we seek AI systems that support, rather than exploit, our fundamental nature as social and emotional beings.

    • Hannah Rose Kirk
    • Iason Gabriel
    • Scott A. Hale
    Comments & OpinionOpen Access
    Humanities and Social Sciences Communications
    Volume: 12, P: 1-9
  • Theories of consciousness have a long and controversial history. One well-known proposal — integrated information theory — has recently been labeled as ‘pseudoscience’, which has caused a heated open debate. Here we discuss the case and argue that the theory is indeed unscientific because its core claims are untestable even in principle.

    • Derek H. Arnold
    • Mark G. Baxter
    • Joel S. Snyder
    Comments & Opinion
    Nature Neuroscience
    Volume: 28, P: 689-693
  • Kynurenine 3-monooxygenase (KMO) regulates levels of neuroactive kynurenine pathway metabolites associated with neurodegeneration. Its inhibition ameliorates disease phenotypes in animal models but current inhibitors are not brain permeable. Through structure-based virtual screening and compound synthesis, Zhang et al. now develop KMO inhibitors that can enter the rodent brain to modulate metabolism in this pathway.

    • Shaowei Zhang
    • Michiyo Sakuma
    • Nigel S. Scrutton
    ResearchOpen Access
    Communications Biology
    Volume: 2, P: 1-10