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Showing 1–4 of 4 results
Advanced filters: Author: Christine Kurihara Clear advanced filters

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • Analysis of bronchoalveolar lavage fluid samples from patients with SARS-CoV-2-induced respiratory failure suggests that SARS-CoV-2 infects alveolar macrophages to cause release of T cell chemoattractants, thereby inducing local inflammatory cytokine release and further T cell activation, ultimately resulting in a positive feedback loop that drives alveolar inflammation.

    • Rogan A. Grant
    • Luisa Morales-Nebreda
    • Ziyou Ren
    Research
    Nature
    Volume: 590, P: 635-641

  • Disease-oriented, introductory medical curricula can help overcome educational and institutional barriers that separate aspiring translational scientists in PhD programs from the world of medicine.

    • Robert Busch
    • Belinda Byrne
    • Elizabeth D Mellins
    Comments & Opinion
    Nature Immunology
    Volume: 7, P: 543-547