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Showing 1–27 of 27 results
Advanced filters: Author: Christoph Gerber Clear advanced filters
  • Stojanov et al. updated and internally validated a prediction model for the occurrence of post-operative shoulder stiffness following primary arthroscopic rotator cuff repair in Switzerland. Their findings support the development of further prediction models for an evidence-based and individualized decision-making in orthopedics.

    • Thomas Stojanov
    • Soheila Aghlmandi
    • Laurent Audigé
    ResearchOpen Access
    Communications Medicine
    Volume: 5, P: 1-8
  • The basal ganglia direct and indirect pathways are classically described as anatomically segregated and functionally opposing. Here the authors describe a non-canonical direct pathway made of axon collaterals to the globus pallidus that promotes motor action.

    • Marie A. Labouesse
    • Arturo Torres-Herraez
    • Christoph Kellendonk
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-20
  • A tunable quantum dot device in Bernal bilayer graphene possesses a spin–valley relaxation time of 38 s at millikelvin temperatures.

    • Artem O. Denisov
    • Veronika Reckova
    • Hadrien Duprez
    ResearchOpen Access
    Nature Nanotechnology
    Volume: 20, P: 494-499
  • A single electron quantum dot in bilayer graphene is a candidate for a spin-valley qubit, however its excited state spectrum has not been determined under relevant conditions. Here the authors accomplish this using time-resolved charge detection technique and set the new upper bound on the inter-valley mixing.

    • Hadrien Duprez
    • Solenn Cances
    • Klaus Ensslin
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-7
  • The invention of the scanning tunnelling microscope 25 years ago, followed by the arrival of the atomic force microscope five years later, were crucial events in the history of nanoscience and nanotechnology. As the recent International Conference on Nanoscience and Technology in Basel made clear, scanning probe microscopes based on these discoveries are still having a tremendous impact on many areas of research.

    • Christoph Gerber
    • Hans Peter Lang
    Comments & Opinion
    Nature Nanotechnology
    Volume: 1, P: 3-5
  • As the evolution of new strains of bacteria that are resistant to antibiotics continues, a nanomechanical approach to understanding the interactions between them could help efforts to develop new antibiotics.

    • François Huber
    • Hans Peter Lang
    • Christoph Gerber
    News & Views
    Nature Nanotechnology
    Volume: 3, P: 645-646
  • Co-inventor of the scanning tunnelling microscope.

    • Christoph Gerber
    Comments & Opinion
    Nature
    Volume: 499, P: 30
  • Measuring the mass of individual microbial cells remains challenging. Here, the authors present a cell balance to monitor the proliferation of single budding yeast cells under culture conditions in real time, showing that single cells increase total mass in multiple linear segments of constant growth rates.

    • Andreas P. Cuny
    • K. Tanuj Sapra
    • Daniel J. Müller
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11
  • There are big uncertainties in the contribution of irrigation to crop yields. Here, the authors use Bayesian model averaging to combine statistical and process-based models and quantify the contribution of irrigation for wheat and maize yields, finding that irrigation alone cannot close yield gaps for a large fraction of global rainfed agriculture.

    • Xuhui Wang
    • Christoph Müller
    • Shilong Piao
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-8
  • RNA modifications play critical roles in gene expression regulation, RNA stability, and translation efficiency, however, the detection of RNA modifications by various sequencing approaches may present differing results. Here, the authors explore several computational methods for the detection of the most researched mRNA modifications, with a view to improving algorithms’ comparability, reliability, and consistency in RNA modification prediction.

    • Jannes Spangenberg
    • Stefan Mündnich
    • Nicolo Alagna
    ResearchOpen Access
    Communications Chemistry
    Volume: 8, P: 1-10
  • The spike protein of the Omicron variant of SARS-CoV-2 has a higher affinity for ACE2 than Delta, and a marked change in its antigenicity increases Omicron’s evasion of therapeutic and vaccine-elicited neutralizing antibodies.

    • Bo Meng
    • Adam Abdullahi
    • Ravindra K. Gupta
    ResearchOpen Access
    Nature
    Volume: 603, P: 706-714
  • Nanomechanical cantilevers can determine the concentration of active drugs in human serum.

    • F. Huber
    • H. P. Lang
    • Ch. Gerber
    News & Views
    Nature Nanotechnology
    Volume: 9, P: 165-167
  • Membrane proteins are central to many biological processes, but it is difficult to measure their interactions with other objects. Sensors based on arrays of resonating microcantilevers have now performed label-free and time-resolved measurements of the interactions between a protein receptor and a bacterial virus under physiological conditions.

    • Thomas Braun
    • Murali Krishna Ghatkesar
    • Martin Hegner
    Research
    Nature Nanotechnology
    Volume: 4, P: 179-185
  • Bian et al. discuss the utility of different variants of scanning probe microscopy, with a focus on scanning tunnelling microscopy and atomic force microscopy. They summarize how the tools are used in the life and physical sciences.

    • Ke Bian
    • Christoph Gerber
    • Ying Jiang
    Reviews
    Nature Reviews Methods Primers
    Volume: 1, P: 1-29
  • Polyamines such as spermidine and putrescine are known to promote autophagy and longevity in fruit flies. Similar to many other organisms, Drosophila also display age-induced memory impairment. Here, Gupta et al. find that a decrease in brain polyamines in aging Drosophila is correlated with age-dependent memory impairment. They also find that polyamines in flies' diet can alleviate this impairment, demonstrating a link between polyamines, autophagy and memory decline.

    • Varun K Gupta
    • Lisa Scheunemann
    • Stephan J Sigrist
    Research
    Nature Neuroscience
    Volume: 16, P: 1453-1460
  • A picobalance consisting of an optically excited microcantilever has been developed and used to measure the masses of individual healthy and virus-infected cells at high temporal and mass resolutions in culture conditions.

    • David Martínez-Martín
    • Gotthold Fläschner
    • Daniel J. Müller
    Research
    Nature
    Volume: 550, P: 500-505
  • Atomic force microscopy (AFM)-based approaches enable the characterization and manipulation of biological and synthetic biointerfaces, including tissues, cells, membranes, proteins, nucleic acid and functional materials. In this Review, the advantages and limitations of imaging, sensing, parameterizing and designing biointerfaces using AFM techniques are discussed.

    • David Alsteens
    • Hermann E. Gaub
    • Daniel J. Müller
    Reviews
    Nature Reviews Materials
    Volume: 2, P: 1-16
  • Mechanobiology describes how biological systems respond to mechanical stimuli. This Review surveys basic principles, advantages and limitations of applying and combining atomic force microscopy-based modalities with complementary techniques to characterize the morphology, mechanical properties and functional response of complex biological systems to mechanical cues.

    • Michael Krieg
    • Gotthold Fläschner
    • Daniel J. Müller
    Reviews
    Nature Reviews Physics
    Volume: 1, P: 41-57