In this Review, Gagneux and colleagues discuss ecological and evolutionary concepts related to the biology and epidemiology of the Mycobacterium tuberculosis complex, including new phylogenetic lineages, host tropism among the various animal-adapted lineages, the evolutionary dynamics of antimicrobial resistance and transmission, as well as within-host diversity and structural genomic variation.
- Galo A. Goig
- Etthel M. Windels
- Sebastien Gagneux