Nature Search

Improved GVHD-free relapse-free survival when rATG/ATLG is used in allo-HCT from matched sibling donors - an EBMT registry study by the Transplant Complications Working Party

Agnieszka Piekarska
Mouad Abouqateb
Zinaida Peric
Research11 Sept 2025
Bone Marrow Transplantation

P: 1-10
Activation of lysosomal iron triggers ferroptosis in cancer

Some cancer cells exhibit high loads of reactive iron in lysosomes, and this feature is exploited by using fentomycin-1, a newly developed small molecule, to induce ferroptosis.

Tatiana Cañeque
Leeroy Baron
Raphaël Rodriguez
ResearchOpen Access07 May 2025
Nature

Volume: 642, P: 492-500
Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition

The endothelial to haematopoietic transition (EHT) is the process where haemogenic endothelium differentiates into haematopoietic stem and progenitor cells (HSPCs). Here the authors use single cell transcriptomics and antibody screening to identify CD44 as a marker of EHT that is required for EHT and HSPC development.

Morgan Oatley
Özge Vargel Bölükbası
Christophe Lancrin
ResearchOpen Access29 Jan 2020
Nature Communications

Volume: 11, P: 1-18
Multiomics approaches disclose very-early molecular and cellular switches during insect-venom allergen-specific immunotherapy: an observational study

Allergen specific immunotherapy (AIT) is both, safe and effective in reducing systemic symptoms of venom allergy in individuals. Here the authors examine the underlying immune cell changes after venom specific AIT in early time points after therapy initiation showing indicative changes in specific immune cell populations.

Dimitrii Pogorelov
Sebastian Felix Nepomuk Bode
Markus Ollert
ResearchOpen Access26 Nov 2024
Nature Communications

Volume: 15, P: 1-22
Outcomes of graft failure after umbilical cord blood transplantation in acute leukemia: a study from Eurocord and the Acute Leukemia Working Party of the EBMT

Frédéric Baron
Annalisa Ruggeri
Mohamad Mohty
Research10 May 2023
Bone Marrow Transplantation

Volume: 58, P: 936-941
Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females

Men are at a greater risk to develop Parkinson’s disease (PD). However, Hefeng and team revealed enhanced cytotoxicity and terminal differentiation in CD8 T cells of early-to-mid stage idiopathic PD, especially for females, using systems immunology.

Christophe M. Capelle
Séverine Ciré
Feng Q. Hefeng
ResearchOpen Access20 Nov 2023
Nature Communications

Volume: 14, P: 1-21
Neutrophil Proteinases in Hydrochloric Acid- and Endotoxin-Induced Acute Lung Injury: Evaluation of Interstitial Protease Activity by in situ Zymography

Andry Van de Louw
Daniel Jean
Christophe Delclaux
Research01 Feb 2002
Laboratory Investigation

Volume: 82, P: 133-145
Combining 3D single molecule localization strategies for reproducible bioimaging

3D single molecule localization microscopy suffers from several experimental biases that degrade the resolution or localization precision. Here the authors present a dual-view detection scheme combining supercritical angle fluorescence and astigmatic imaging to obtain precise and unbiased 3D super resolution images.

Clément Cabriel
Nicolas Bourg
Sandrine Lévêque-Fort
ResearchOpen Access30 Apr 2019
Nature Communications

Volume: 10, P: 1-10
PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains T_reg homeostasis during ageing

In this work, Danileviciute, Zeng et al. provide new insights into the regulation of the PDH complex by PARK7/DJ-1 and show its relevance in T_reg homeostasis during ageing.

Egle Danileviciute
Ni Zeng
Feng Q. Hefeng
Research26 May 2022
Nature Metabolism

Volume: 4, P: 589-607
An experimental study focusing on mindfulness to capture how our contacts with dogs can promote human well-being

Catherine E. Amiot
Mylène Quervel-Chaumette
Brock Bastian
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-17
Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis

Blockade of the C5a–C5aR1 axis using anti-C5aR1 monoclonal antibodies prevented inflammation associated with COVID-19.

Julien Carvelli
Olivier Demaria
Eric Vivier
Research29 Jul 2020
Nature

Volume: 588, P: 146-150
Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis

Trypanosoma cruzi infection causes Chagas disease, but mechanisms underlying pathogenesis are unclear. Here, Silva et al. show that canonical PI3Kγ signaling in myeloid cells restricts T. cruzi infection in mice and that high PIK3CG expression correlates with low parasite levels in human Chagas’ hearts.

Maria C. Silva
Marcela Davoli-Ferreira
Thiago M. Cunha
ResearchOpen Access17 Apr 2018
Nature Communications

Volume: 9, P: 1-14
Retinoid X receptor gamma signaling accelerates CNS remyelination

The authors report a transcriptional profile of the discrete stages of spontaneous remyelination following toxin-induced focal demyelination in rats. They find an enrichment of retinoid X receptor (RXR) signaling pathways over the course of remyelination and show that RXR activation stimulates oligodendrocyte differentiation to enhance remyelination.

Jeffrey K Huang
Andrew A Jarjour
Robin J M Franklin
Research05 Dec 2010
Nature Neuroscience

Volume: 14, P: 45-53
AKT2 is essential to maintain podocyte viability and function during chronic kidney disease

Rapamycin (also known as sirolimus) is a potent immunosuppressive drug that is often used after organ transplant to prevent rejection, but it also can cause kidney dysfunction. Fabiola Terzi and her colleagues now show this side effect of rapamycin is due to targeting of mTORC2 and suppression of AKT2 activity in podocytes. They also show that AKT2 normally acts to maintain podocyte viability and structure during chronic kidney disease.

Guillaume Canaud
Frank Bienaimé
Fabiola Terzi
Research22 Sept 2013
Nature Medicine

Volume: 19, P: 1288-1296
Profiling brain morphology for autism spectrum disorder with two cross-culture large-scale consortia

Using the lifespan brain chart and two large-scale cross-cultural consortia (ABIDE and CABIC), we disentangle the heterogeneity of brain morphology in ASD into two structural impairment pathways that could disrupt sensory to association functions.

Xue-Ru Fan
Ye He
Xi-Nian Zuo
ResearchOpen Access05 Aug 2025
Communications Biology

Volume: 8, P: 1-16
Inactivation of the p53 pathway in retinoblastoma

Nikia A. Laurie
Stacy L. Donovan
Michael A. Dyer
Research02 Nov 2006
Nature

Volume: 444, P: 61-66
A Single Dose, Randomized, Controlled Proof-Of-Mechanism Study of a Novel Vasopressin 1a Receptor Antagonist (RG7713) in High-Functioning Adults with Autism Spectrum Disorder

Daniel Umbricht
Marta del Valle Rubido
Paulo Fontoura
ResearchOpen Access06 Oct 2016
Neuropsychopharmacology

Volume: 42, P: 1914-1923
Major discrepancy between factual antibiotic resistance and consumption in South of France: analysis of 539,037 bacterial strains

Ousmane Oumou Diallo
Sophie Alexandra Baron
Jean-Marc Rolain
ResearchOpen Access26 Oct 2020
Scientific Reports

Volume: 10, P: 1-9
Inferring upstream regulatory genes of FOXP3 in human regulatory T cells from time-series transcriptomic data

Stefano Magni
Rucha Sawlekar
Jorge Gonçalves
ResearchOpen Access29 May 2024
npj Systems Biology and Applications

Volume: 10, P: 1-13
Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis

Zhong-Yi Wang
Adrian Keogh
Florian Nigsch
ResearchOpen Access29 Sept 2021
Scientific Reports

Volume: 11, P: 1-15
Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry

Michael D Walsh
Daniel D Buchanan
Joanne P Young
Research10 Feb 2012
Modern Pathology

Volume: 25, P: 722-730
Acute pathophysiological myocardial changes following intra-cardiac electrical shocks using a proteomic approach in a sheep model

Alexandre Bodin
Valérie Labas
Nicolas Clementy
ResearchOpen Access20 Nov 2020
Scientific Reports

Volume: 10, P: 1-12
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages

Els Wauters
Pierre Van Mol
Diether Lambrechts
ResearchOpen Access21 Jan 2021
Cell Research

Volume: 31, P: 272-290
Stimulation of P2Y11 receptor protects human cardiomyocytes against Hypoxia/Reoxygenation injury and involves PKCε signaling pathway

Lauriane Benoist
Stéphanie Chadet
Fabrice Ivanes
ResearchOpen Access12 Aug 2019
Scientific Reports

Volume: 9, P: 1-11
Rock inhibition promotes Na_V1.5 sodium channel-dependent SW620 colon cancer cell invasiveness

Lucile Poisson
Osbaldo Lopez-Charcas
Driffa Moussata
ResearchOpen Access07 Aug 2020
Scientific Reports

Volume: 10, P: 1-14
Leaf economics and slow-fast adaptation across the geographic range of Arabidopsis thaliana

Kevin Sartori
François Vasseur
Denis Vile
ResearchOpen Access24 Jul 2019
Scientific Reports

Volume: 9, P: 1-12
A longitudinal resource for population neuroscience of school-age children and adolescents in China

Xue-Ru Fan
Yin-Shan Wang
Xi-Nian Zuo
ResearchOpen Access21 Aug 2023
Scientific Data

Volume: 10, P: 1-24

Search

Improved GVHD-free relapse-free survival when rATG/ATLG is used in allo-HCT from matched sibling donors - an EBMT registry study by the Transplant Complications Working Party

Activation of lysosomal iron triggers ferroptosis in cancer

Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition

Multiomics approaches disclose very-early molecular and cellular switches during insect-venom allergen-specific immunotherapy: an observational study

Outcomes of graft failure after umbilical cord blood transplantation in acute leukemia: a study from Eurocord and the Acute Leukemia Working Party of the EBMT

Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females

Neutrophil Proteinases in Hydrochloric Acid- and Endotoxin-Induced Acute Lung Injury: Evaluation of Interstitial Protease Activity by in situ Zymography

Combining 3D single molecule localization strategies for reproducible bioimaging

PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains T_reg homeostasis during ageing

An experimental study focusing on mindfulness to capture how our contacts with dogs can promote human well-being

Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis

Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis

Retinoid X receptor gamma signaling accelerates CNS remyelination

AKT2 is essential to maintain podocyte viability and function during chronic kidney disease

Profiling brain morphology for autism spectrum disorder with two cross-culture large-scale consortia

Inactivation of the p53 pathway in retinoblastoma

A Single Dose, Randomized, Controlled Proof-Of-Mechanism Study of a Novel Vasopressin 1a Receptor Antagonist (RG7713) in High-Functioning Adults with Autism Spectrum Disorder

Major discrepancy between factual antibiotic resistance and consumption in South of France: analysis of 539,037 bacterial strains

Inferring upstream regulatory genes of FOXP3 in human regulatory T cells from time-series transcriptomic data

Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis

Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry

Acute pathophysiological myocardial changes following intra-cardiac electrical shocks using a proteomic approach in a sheep model

Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages

Stimulation of P2Y11 receptor protects human cardiomyocytes against Hypoxia/Reoxygenation injury and involves PKCε signaling pathway

Rock inhibition promotes Na_V1.5 sodium channel-dependent SW620 colon cancer cell invasiveness

Leaf economics and slow-fast adaptation across the geographic range of Arabidopsis thaliana

A longitudinal resource for population neuroscience of school-age children and adolescents in China

Search

Quick links

Search

Filter By:

Search

Quick links