Nature Search

Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein

Christopher Southgate
Maria L. Zapp
Michael R. Green
Research14 Jun 1990
Nature

Volume: 345, P: 640-642
Telomere length alterations and ATRX/DAXX loss in pituitary adenomas

Christopher M. Heaphy
Wenya Linda Bi
Fausto J. Rodriguez
Research18 Mar 2020
Modern Pathology

Volume: 33, P: 1475-1481
Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors

Paloma Cejas
Yotam Drier
Ramesh A. Shivdasani
Amendments and Corrections09 Sept 2019
Nature Medicine

Volume: 25, P: 1627
Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors

Epigenetic states reminiscent of the cell of origin define clinically relevant markers for stratification of patients with pancreatic neuroendocrine cancer.

Paloma Cejas
Yotam Drier
Ramesh A. Shivdasani
Research01 Jul 2019
Nature Medicine

Volume: 25, P: 1260-1265
Prognostic and therapeutic potential of senescent stromal fibroblasts in prostate cancer

Senescent stromal fibroblasts exhibit a senescence-associated secretory phenotype, which can promote prostate cancer development, progression and resistance to therapy. Targeting senescent cells via senotherapeutics might be an attractive preventive or therapeutic option for prostate cancer.

Joakin O. Mori
Isra Elhussin
Christopher M. Heaphy
Reviews31 Oct 2023
Nature Reviews Urology

Volume: 21, P: 258-273
Telomeres and telomerase in prostate cancer development and therapy

Aberrations in telomere biology occur in prostate cancer tumorigenesis and progression. Graham and Meeker review the role of shortened telomeres in prostate tumour pathogenesis, including genomic instability and mutations. They describe the clinical utility of assessment of telomere dysfunction and the therapeutic potential of treatments targeting telomerase and telomeres.

Mindy Kim Graham
Alan Meeker
Reviews04 Jul 2017
Nature Reviews Urology

Volume: 14, P: 607-619
Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors

Roeland F de Wilde
Christopher M Heaphy
Karen E Matsukuma
Research11 May 2012
Modern Pathology

Volume: 25, P: 1033-1039
Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias

Seung-Mo Hong
Christopher M Heaphy
Michael Goggins
Research24 Sept 2010
Modern Pathology

Volume: 24, P: 256-266
Chromophobe hepatocellular carcinoma with abrupt anaplasia: a proposal for a new subtype of hepatocellular carcinoma with unique morphological and molecular features

Laura D Wood
Christopher M Heaphy
Michael S Torbenson
Research03 May 2013
Modern Pathology

Volume: 26, P: 1586-1593
Shorter telomeres in luminal B, HER-2 and triple-negative breast cancer subtypes

Christopher M Heaphy
Andrea Proctor Subhawong
Alan K Meeker
Research05 Nov 2010
Modern Pathology

Volume: 24, P: 194-200
SMARCAL1 loss and alternative lengthening of telomeres (ALT) are enriched in giant cell glioblastoma

Jacqueline A. Brosnan-Cashman
Christine M. Davis
Christopher M. Heaphy
Research08 Jun 2021
Modern Pathology

Volume: 34, P: 1810-1819
Convolutional neural networks for accurate real-time diagnosis of oral epithelial dysplasia and oral squamous cell carcinoma using high-resolution in vivo confocal microscopy

Rishi S. Ramani
Ivy Tan
Tami Yap
ResearchOpen Access20 Jan 2025
Scientific Reports

Volume: 15, P: 1-13
Subependymal giant cell astrocytoma-like astrocytoma: a neoplasm with a distinct phenotype and frequent neurofibromatosis type-1-association

Doreen N. Palsgrove
Jacqueline A. Brosnan-Cashman
Fausto J. Rodriguez
Research04 Jul 2018
Modern Pathology

Volume: 31, P: 1787-1800
Generation and characterization of a cell line from an intraductal tubulopapillary neoplasm of the pancreas

Using three-dimensional followed by two-dimensional culture, the authors generated the first reported cell line from a human pancreatic intraductal tubulopapillary neoplasm, a distinct precancerous lesion. They performed in-depth molecular analysis of the cell line and characterized its tumorigenic potential using multiple in vitro and in vivo assays.

Matthäus Felsenstein
Maria A. Trujillo
Laura D. Wood
Research31 Jan 2020
Laboratory Investigation

Volume: 100, P: 1003-1013
The alternative lengthening of telomeres phenotype in breast carcinoma is associated with HER-2 overexpression

Andrea Proctor Subhawong
Christopher M Heaphy
Alan K Meeker
Research04 Sept 2009
Modern Pathology

Volume: 22, P: 1423-1431

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