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Nature Microbiology (2)
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Advanced filters: Author: Christopher Nötzel Clear advanced filters

scRNA-seq reveals transcriptional plasticity of var gene expression in Plasmodium falciparum for host immune avoidance

Single-cell transcriptomics revealed that malaria parasites have unexpected flexibility in surface antigen expression, potentially providing parasites with greater adaptive capacity to maintain chronic asymptomatic infections.

Francesca Florini
Joseph E. Visone
Kirk W. Deitsch
Research16 May 2025
Nature Microbiology

Volume: 10, P: 1417-1430
Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum

The manipulation of expression of PfAP2-G, the master regulator of gametocytogenesis in malaria parasites, reveals that in addition to the canonical next cycle conversion route, sexual conversion can occur without additional replication (that is, within the same cycle).

Cristina Bancells
Oriol Llorà-Batlle
Alfred Cortés
Research26 Nov 2018
Nature Microbiology

Volume: 4, P: 144-154
Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites

Highly parallel single-cell transcriptome profiling of Plasmodium falciparum blood stages provides insight into the role AP2-G plays in early sexual development of this eukaryotic pathogen.

Asaf Poran
Christopher Nötzel
Björn F. C. Kafsack
Research25 Sept 2017
Nature

Volume: 551, P: 95-99