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Showing 1–3 of 3 results
Advanced filters: Author: Chrystel Lafont Clear advanced filters
  • A bivalent biparatopic nanobody penetrates the brain, binds to and potentiates the activity of homodimeric metabotropic glutamate receptor 2, correcting cognitive deficits in two preclinical mouse models with endophenotypes resulting from NMDA receptor hypofunction.

    • Mathieu Oosterlaken
    • Angelina Rogliardo
    • Philippe Rondard
    ResearchOpen Access
    Nature
    Volume: 645, P: 262-270
  • The hypothalamus and pituitary gland can undergo many functional adaptations to control hormonal output. In this Review, the authors describe our current understanding of the neuroendocrine changes in these structures that maximize reproductive success, and highlight how new imaging techniques have transformed our interpretation of these processes.

    • Paul Le Tissier
    • Pauline Campos
    • Patrice Mollard
    Reviews
    Nature Reviews Endocrinology
    Volume: 13, P: 257-267
  • Experience-dependent plasticity and functional adaptation are thought to be restricted to the central nervous and immune systems. This study shows that long-lasting experience-dependent plasticity is a key feature of endocrine cell networks, allowing improved tissue function and hormone output following repeat demand.

    • David J. Hodson
    • Marie Schaeffer
    • Patrice Mollard
    ResearchOpen Access
    Nature Communications
    Volume: 3, P: 1-10