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Showing 1–1 of 1 results
Advanced filters: Author: Chuao-chao Lu Clear advanced filters

  • The bacterial tetracycline resistance protein Tet(O) binds to the ribosome, preventing tetracycline from inhibiting translation. Using cryo-electron microscopic reconstruction, the authors present an atomic model of Tet(O) bound to the 70S ribosome, and reveal how Tet(O) promotes antibiotic resistance.

    • Wen Li
    • Gemma C. Atkinson
    • Joachim Frank
    Research
    Nature Communications
    Volume: 4, P: 1-8