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Showing 1–7 of 7 results
Advanced filters: Author: Ciro Chiappini Clear advanced filters

  • Arrays of silicon nanoneedles are used to generate molecular replicas of live brain tissue for longitudinal spatial lipidomic classification via desorption electrospray ionization mass spectrometry imaging of gliomas and to monitor the responses of the tumours to chemotherapy.

    • Chenlei Gu
    • Davide Alessandro Martella
    • Ciro Chiappini
    ResearchOpen Access
    Nature Nanotechnology
    Volume: 20, P: 1262-1272

  • Prelithiation can introduce controllable amounts of lithium within porous silicon, however it yields a highly reactive material unsuitable for biomedicine. In this study, the authors present a strategy to lithiate porous silicon nanowires, resulting in a biocompatible and bioresorbable material.

    • Martti Kaasalainen
    • Ran Zhang
    • Ciro Chiappini
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-16

  • This tutorial describes how to develop a nanoinjection workflow, including the selection of nanoneedle devices, approaches to loading cargo, strategies for interfacing to biological systems and assays to evaluate the efficacy of intracellular delivery.

    • Ciro Chiappini
    • Yaping Chen
    • Roey Elnathan
    Reviews
    Nature Protocols
    Volume: 16, P: 4539-4563

  • Achieving effective collaboration in bioengineering is an art and a science. Here we outline strategies for building and sustaining interdisciplinary partnerships, and outline challenges, opportunities and funding options for establishing and strengthening collaborative research.

    • Nicolas H. Voelcker
    • Andy Tay
    • Roey Elnathan
    Comments & Opinion
    Nature Reviews Bioengineering
    Volume: 3, P: 531-533

  • Vertical nanoprobes are high-aspect-ratio nanomaterials used to manipulate and interrogate cells with high spatiotemporal resolution and limited perturbation. This Review discusses the design principles to establish effective nanoprobe biointerfaces for drug delivery, intracellular sampling and sensing, biophysical interaction and bioelectronics.

    • Roey Elnathan
    • Maria Grazia Barbato
    • Ciro Chiappini
    Reviews
    Nature Reviews Materials
    Volume: 7, P: 953-973

  • Nanoneedle start-ups are traversing the biotech valley of death — from fundamental university research into commercial development in advanced therapeutics and diagnostics. How can academics make the most of this opportunity?

    • Roey Elnathan
    • Andy Tay
    • Ciro Chiappini
    Comments & Opinion
    Nature Nanotechnology
    Volume: 17, P: 807-811