Nature Search

The evolutionary history and timeline of mites in ancient soils

Pavel B. Klimov
Vasiliy B. Kolesnikov
Henk R. Braig
ResearchOpen Access19 Apr 2025
Scientific Reports

Volume: 15, P: 1-15
Author Correction: Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint

Judy C. Boughey
Michael D. Alvarado
Kathleen Kemmer
Amendments and CorrectionsOpen Access02 Jan 2019
npj Breast Cancer

Volume: 5, P: 1
DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution

Integrated multi-omic analyses using samples from the TRACERx study highlight cross-talk between DNA hypermethylation and genomic lesions in non-small cell lung cancer.

Francisco Gimeno-Valiente
Carla Castignani
Nnennaya Kanu
ResearchOpen Access10 Sept 2025
Nature Genetics

Volume: 57, P: 2226-2237
Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis

Preclinical studies indicate that myeloproliferative neoplasms (MPN) may be sensitive to the estrogen receptor modulator, tamoxifen. Here, the authors present a phase II clinical trial reporting the efficacy of tamoxifen in MPN and analysis of peripheral haematopoietic stem cells to identify potential predictive signatures of responders.

Zijian Fang
Giuditta Corbizi Fattori
Simón Méndez-Ferrer
ResearchOpen Access25 Nov 2023
Nature Communications

Volume: 14, P: 1-21
Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia

Studies with patient derived xenografts are hampered by factors such as genetic variability and sample availability. Here, the authors generate a leukemia mouse model by lentiviral transduction of normal human cord blood and show an oncogenic role of HOXB genes.

Manabu Kusakabe
Ann Chong Sun
Andrew P. Weng
ResearchOpen Access02 Jul 2019
Nature Communications

Volume: 10, P: 1-15
DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts

Cancer cells within the same tumour are heterogeneous in their tumorigenic potential, differentiation status and sensitivity to treatments. Here Nguyen et al. use a sensitive DNA barcoding method to characterize the diversity of clonal growth behaviour within human breast tumours.

Long V. Nguyen
Claire L. Cox
Connie J. Eaves
ResearchOpen Access23 Dec 2014
Nature Communications

Volume: 5, P: 1-9
Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing

The transcription factor Nkx2.5 is essential for heart development. Here, the authors identify a previously unknown expression domain for Nkx2.5 in the emu wing and explore its role in diminished wing bud development in the flightless emu, compared with three other birds that have functional wings.

Peter G. Farlie
Nadia M. Davidson
Craig A. Smith
ResearchOpen Access25 Jul 2017
Nature Communications

Volume: 8, P: 1-12
Differentiation of human embryonic stem cells to HOXA⁺ hemogenic vasculature that resembles the aorta-gonad-mesonephros

Human embryonic stem cells are differentiated to cells similar to the embryonic aorta-gonad-mesonephros, which gives rise to hematopoietic stem cells.

Elizabeth S Ng
Lisa Azzola
Andrew G Elefanty
Research17 Oct 2016
Nature Biotechnology

Volume: 34, P: 1168-1179
Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells

The first formal evidence of the shared and independent ability of basal cells and luminal pro-genitors isolated from normal human mammary tissue and transduced with a single oncogene to initiate tumorigeneses when introduced into mice.

Long V. Nguyen
Davide Pellacani
Connie J. Eaves
Research02 Dec 2015
Nature

Volume: 528, P: 267-271
NKX2-5^eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

A human embryonic stem cell line expressing a fluorescent reporter of cardiac differentiation is described. The authors use this tool to optimize differentiation methods and to identify cell-surface markers in the cardiac lineage.

David A Elliott
Stefan R Braam
Edouard G Stanley
Research23 Oct 2011
Nature Methods

Volume: 8, P: 1037-1040
Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint

Judy C. Boughey
Michael D. Alvarado
Kathleen Kemmer
ReviewsOpen Access17 Aug 2018
npj Breast Cancer

Volume: 4, P: 1-5
Comparison of in silico strategies to prioritize rare genomic variants impacting RNA splicing for the diagnosis of genomic disorders

Charlie Rowlands
Huw B. Thomas
Jamie M. Ellingford
ResearchOpen Access18 Oct 2021
Scientific Reports

Volume: 11, P: 1-11

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The evolutionary history and timeline of mites in ancient soils

Author Correction: Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint

DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution

Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis

Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia

DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenografts

Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing

Differentiation of human embryonic stem cells to HOXA⁺ hemogenic vasculature that resembles the aorta-gonad-mesonephros

Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells

NKX2-5^eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint

Comparison of in silico strategies to prioritize rare genomic variants impacting RNA splicing for the diagnosis of genomic disorders

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