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Showing 1–5 of 5 results

Advanced filters: Author: Claire Smillie Clear advanced filters

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

Richard Houlston and colleagues report a genome-wide association study for colorectal cancer. They report three loci newly associated with colorectal cancer, bringing the total number of common susceptibility loci to 20.

Malcolm G Dunlop
Sara E Dobbins
Richard S Houlston
Research27 May 2012
Nature Genetics

Volume: 44, P: 770-776
A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice

Interactions between the host immune response and the commensal microbiota play essential roles in health and disease. Here the authors identify a population of MHC class II, innate like, commensal reactive cells in the gut of mice and humans.

Carl-Philipp Hackstein
Dana Costigan
Emily E. Thornton
ResearchOpen Access03 Dec 2022
Nature Communications

Volume: 13, P: 1-19
The tuatara genome reveals ancient features of amniote evolution

The approximately 5-Gb tuatara (Sphenodon punctatus) genome assembly provides a resource for analysing amniote evolution, and highlights the imperative for meaningful cultural engagement with Indigenous communities in genome-sequencing endeavours.

Neil J. Gemmell
Kim Rutherford
Haydn Edmonds
ResearchOpen Access05 Aug 2020
Nature

Volume: 584, P: 403-409
Publisher Correction: The tuatara genome reveals ancient features of amniote evolution

Neil J. Gemmell
Kim Rutherford
Haydn Edmonds
Amendments and CorrectionsOpen Access18 Aug 2020
Nature

Volume: 585, P: E3
Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer

Maria N. Timofeeva
Ben Kinnersley
Richard S. Houlston
ResearchOpen Access10 Nov 2015
Scientific Reports

Volume: 5, P: 1-10