Epigenomic and transcriptomic analyses reveal that, during mouse spermatogenesis, the H3K79 methyltransferase DOT1L has opposite effects on autosomal and X-linked gene expression depending on local chromatin enrichment in H3K79me2 and in H3K27me3.
- Manon Coulée
- Alberto de la Iglesia
- Laïla El Khattabi