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Showing 1–7 of 7 results
Advanced filters: Author: Claude B Sirlin Clear advanced filters
  • The NIMBLE biomarker qualification project evaluated the diagnostic performance of five blood-based biomarkers in a cohort of individuals with non-alcoholic fatty liver disease and showed good discriminative performance over commonly used laboratory tests in detecting various stages of non-alcoholic steatohepatitis progression.

    • Arun J. Sanyal
    • Sudha S. Shankar
    • Roberto A. Calle
    ResearchOpen Access
    Nature Medicine
    Volume: 29, P: 2656-2664
  • Development of cirrhosis in individuals with non-alcoholic fatty liver disease can predict mortality. Here the authors used a unique twin and family cohort to identify a gut microbiome-derived 16sRNA signature that can detect cirrhosis in individuals with non-alcoholic fatty liver disease.

    • Cyrielle Caussy
    • Anupriya Tripathi
    • Rohit Loomba
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-9
  • In the past decade, there have been significant advances in the three techniques classically used for liver imaging—ultrasonography, CT and MRI. In this Review, the authors highlight the advances in these techniques that apply to the assessment of focal and diffuse liver disease, including the development of hardware, software, processing algorithms, and procedural innovations.

    • Okka W Hamer
    • Klaus Schlottmann
    • Stefan Feuerbach
    Reviews
    Nature Clinical Practice Gastroenterology & Hepatology
    Volume: 4, P: 215-228
  • Nonalcoholic fatty liver disease is characterized by excess accumulation of fat in hepatocytes, which can be accompanied by inflammation, cell injury and fibrosis. Here, Brunt et al. explain the pathophysiology, the current limitations in management options and the avenues for progress.

    • Elizabeth M. Brunt
    • Vincent W.-S. Wong
    • Mary E. Rinella
    Reviews
    Nature Reviews Disease Primers
    Volume: 1, P: 1-22