Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–6 of 6 results
Advanced filters: Author: Cody Geary Clear advanced filters

  • Using cryogenic electron tomography (cryo-ET) and individual-particle cryo-electron tomography (IPET), non-averaged ternary structures of individual RNA origami 6HBC particles were determined, allowing observation of structural diversity and self-folding dynamics during the maturation process after transcription.

    • Jianfang Liu
    • Ewan K. S. McRae
    • Gang Ren
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • RNA nanostructures can be designed to fold during transcription, but the solution structure has remained elusive. Here the authors use cryogenic electron microscopy to determine the structure of a panel of RNA origami shapes and uncover the design and folding principles.

    • Ewan K. S. McRae
    • Helena Østergaard Rasmussen
    • Ebbe Sloth Andersen
    Research
    Nature Nanotechnology
    Volume: 18, P: 808-817

  • RNA origami can be used for the modular design of RNA nanoscaffolds but can be challenging to design. Newly developed computer-aided design software has now been shown to improve the folding yield of kilobase-sized RNA origami. These structures fold from a single strand during transcription by an RNA polymerase, and are able to position small molecules and protein components with nanoscale precision.

    • Cody Geary
    • Guido Grossi
    • Ebbe S. Andersen
    Research
    Nature Chemistry
    Volume: 13, P: 549-558

  • Whereas synthetic DNA nanostructures are widely studied, the use of RNA as a structural building block is much less common. Now, it has been shown that tRNA molecules can be designed to assemble into a rigid and thermally stable square antiprism structure that may prove useful for delivery applications inside cells.

    • Isil Severcan
    • Cody Geary
    • Luc Jaeger
    Research
    Nature Chemistry
    Volume: 2, P: 772-779

  • Homooligomerization systems can be used to construct nanoarchitectures and to aid understanding of natural analogues. But the formation of such artificial systems with structural diversity and complexity comparable to that of biological systems is challenging. Now, an artificial branched kissing-loop motif has been designed, which links tiles folded from a single strand of RNA to give diverse homooligomeric nanostructures.

    • Di Liu
    • Cody W. Geary
    • Yossi Weizmann
    Research
    Nature Chemistry
    Volume: 12, P: 249-259