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Showing 1–4 of 4 results
Advanced filters: Author: Conor Gruber Clear advanced filters

  • Somatically determined preferential allelic expression of select genes that when mutated cause inborn errors of immunity corresponds with disease phenotypes, suggesting that the penetrance and expressivity of monogenic disorders is also dependent on the ‘transcriptotype’.

    • O’Jay Stewart
    • Conor Gruber
    • Dusan Bogunovic
    Research
    Nature
    Volume: 637, P: 1186-1197

  • Dysregulated immune features in a patient with a homozygous loss-of-function mutation in PDCD1 suggest that IL-6, IL-23, STAT3 and RORγT might be potential targets for treatment of PD-1 blockade-induced autoimmunity.

    • Masato Ogishi
    • Rui Yang
    • Jean-Laurent Casanova
    Research
    Nature Medicine
    Volume: 27, P: 1646-1654

  • This Comment article from the Precision Immunology Institute at the Icahn School of Medicine (PrIISM), New York, describes their efforts to provide critical reviews of COVID-19 articles posted daily on the preprint servers bioRxiv and medRxiv.

    • Nicolas Vabret
    • Robert Samstein
    • Uri Laserson
    Comments & Opinion
    Nature Reviews Immunology
    Volume: 20, P: 338