This work reports an analysis of primary and secondary immune responses in ten women infected with ZIKV for 224 days following an acute symptomatic Zika virus infection. CD4+ T-cell responses broadly targeted the whole Zika genome, whereas CD8+ T cells were strongly biased towards non-structural proteins.
- Pierre Tonnerre
- Juliana G. Melgaço
- Lia L. Lewis-Ximenez