The role of ATM in DNA double-strand break (DSB) signalling is well established, but its function in the repair process remains controversial. Here, Álvarez-Quilón et al.show that ATM acts in the joining of blocked DSBs, uncovering DNA end structure as a key factor determining ATM involvement in DSB repair.
- Alejandro Álvarez-Quilón
- Almudena Serrano-Benítez
- Felipe Cortés-Ledesma
