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Showing 1–8 of 8 results

Advanced filters: Author: Crystal M. Alfred Clear advanced filters

Intrathecal onasemnogene abeparvovec in treatment-naive patients with spinal muscular atrophy: a phase 3, randomized controlled trial

The phase 3 STEER trial showed that a single intrathecal dose of onasemnogene abeparvovec significantly improved motor function in children and adolescents with spinal muscular atrophy versus sham, with a similar and acceptable safety profile.

Crystal M. Proud
Dũng Chí Vũ
Yuh-Jyh Jong
ResearchOpen Access08 Dec 2025
Nature Medicine

Volume: 32, P: 481-487
Atomically thin half-van der Waals metals enabled by confinement heteroepitaxy

Single-crystal 2D metals are stabilized at the interface between epitaxial graphene and silicon carbide, with strong internal gradients in bonding character. The confined 2D metals demonstrate compelling superconducting properties.

Natalie Briggs
Brian Bersch
Joshua A. Robinson
Research10 Mar 2020
Nature Materials

Volume: 19, P: 637-643
Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD

A comprehensive analysis of the cell-specific molecular regulatory mechanisms underlying post-traumatic stress disorder in the human prefrontal cortex.

Ahyeon Hwang
Mario Skarica
Matthew J. Girgenti
ResearchOpen Access18 Jun 2025
Nature

Volume: 643, P: 744-754
Profiling neuronal methylome and hydroxymethylome of opioid use disorder in the human orbitofrontal cortex

Opioid use disorder (OUD) is influenced by genetic and environmental factors. Here, authors use a multi-omics approach to reveal DNA hydroxymethylation as an important gene regulatory mechanism for OUD in the human brain.

Gregory Rompala
Sheila T. Nagamatsu
Janitza L. Montalvo-Ortiz
ResearchOpen Access28 Jul 2023
Nature Communications

Volume: 14, P: 1-14
Malaria is a cause of iron deficiency in African children

A genetic link suggests that interventions that halve the risk of malaria episodes could reduce the prevalence of iron deficiency in African children by nearly 50%.

John Muthii Muriuki
Alexander J. Mentzer
Sarah H. Atkinson
Research22 Feb 2021
Nature Medicine

Volume: 27, P: 653-658
Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model

Chris Varghese
Luke Peters
Caroline Reinke
ResearchOpen Access26 Aug 2025
npj Digital Medicine

Volume: 8, P: 1-16
A trial comparing continuous positive airway pressure (CPAP) devices in preterm infants

Carl H. Backes
Jennifer N. Cooper
Charles V. Smith
ResearchOpen Access20 May 2020
Journal of Perinatology

Volume: 40, P: 1193-1201
Histone H2AX promotes metastatic progression by preserving glycolysis via hexokinase-2

Yue Liu
Haojian Li
Urbain Weyemi
ResearchOpen Access08 Mar 2022
Scientific Reports

Volume: 12, P: 1-12