Nature Search

Stressed Aluminium

E. A. OWEN
Y. H. LIU
D. P. MORRIS
Research01 May 1948
Nature

Volume: 161, P: 681-682
An aquatic sloth from the Pliocene of Peru

C. de Muizon
H. G. McDonald
Research18 May 1995
Nature

Volume: 375, P: 224-227
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation

Owen Sansom and colleagues show that conditional deletion of Pten specifically from the small intestinal epithelium in mice does not disrupt normal tissue architecture, but in the context of Apc deficiency leads to rapid development of adenocarcinoma. These findings suggest that Pten does not serve a rate-limiting, intrinsic role in regulating normal intestinal stem cell physiology.

Victoria Marsh
Douglas J Winton
Alan R Clarke
Research16 Nov 2008
Nature Genetics

Volume: 40, P: 1436-1444
Visitation of the Royal Observatory, Greenwich

A. C. D. CROMMELIN
News14 Jun 1930
Nature

Volume: 125, P: 909-910
Structural insights into the function of type VI secretion system TssA subunits

TssA is an important component of the bacterial type VI secretion system (T6SS). Here, Dix et al. integrate structural, phylogenetic and functional analysis of the TssA subunits, providing new insights into their role in T6SS assembly and function.

Samuel R. Dix
Hayley J. Owen
Mark S. Thomas
ResearchOpen Access12 Nov 2018
Nature Communications

Volume: 9, P: 1-16
CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Alterations in the tumour suppressor genes STK11 and/or KEAP1 can identify patients with advanced non-small-cell lung cancer who are likely to benefit from combinations of PD-(L)1 and CTLA4 immune checkpoint inhibitors added to chemotherapy.

Ferdinandos Skoulidis
Haniel A. Araujo
John V. Heymach
ResearchOpen Access09 Oct 2024
Nature

Volume: 635, P: 462-471
Placental Barrier to Maternal Cells

W. D. BILLINGTON
D. R. S. KIRBY
ANNE MCLAREN
Research15 Nov 1969
Nature

Volume: 224, P: 704-706
Plant survival

Owen D. V. Sholes
Research20 Oct 1994
Nature

Volume: 371, P: 661
Transparent displays enabled by resonant nanoparticle scattering

Transparent displays find increasing use in a variety of applications that project information to a viewer. Here, Hsu and colleagues realize a transparent display that uses nanoparticles for a wavelength-selective scattering of incoming light.

Chia Wei Hsu
Bo Zhen
Marin Soljačić
Research21 Jan 2014
Nature Communications

Volume: 5, P: 1-6
Crystallographic Evidence for Ade-AdeH Hydrogen-bonded Pairs in a Cobalt-Adenine Complex

P. DE MEESTER
D. M. L. GOODGAME
A. C. SKAPSKI
Research23 Mar 1973
Nature

Volume: 242, P: 257-258
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Hydrogen escaping from a pair of exoplanets smaller than Neptune

Ongoing hydrogen loss from two sibling exoplanets provides support for the role of such hydrogen loss in the evolution of close-orbiting sub-Neptunes.

R. O. Parke Loyd
Ethan Schreyer
David R. Ardila
Research12 Feb 2025
Nature

Volume: 638, P: 636-639
A striatal interneuron circuit for continuous target pursuit

Many natural behaviours involve tracking of a target in space. Here, the authors describe a task to assess this behaviour in mice and use in vivo electrophysiology, calcium imaging, optogenetics, and chemogenetics to investigate the role of the striatum in target pursuit.

Namsoo Kim
Haofang E. Li
Henry H. Yin
ResearchOpen Access20 Jun 2019
Nature Communications

Volume: 10, P: 1-14
Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis

Early intermittent feeding of mice with a high-cholesterol Western-type diet accelerates atherosclerosis compared with late continuous exposure to the Western-type diet, despite similar cumulative circulating LDL-C levels.

Minoru Takaoka
Xiaohui Zhao
Ziad Mallat
ResearchOpen Access04 Sept 2024
Nature

Volume: 634, P: 457-465
A new dopaminergic prodrug

A. S. HORN
D. DE KASTE
A. WESTERBRINK
Research23 Nov 1978
Nature

Volume: 276, P: 405-407
The origin and relative abundances of C, N and the noble gases on the terrestrial planets and in meteorites

D. D. BOGARD
E. K. GIBSON JR
Research12 Jan 1978
Nature

Volume: 271, P: 150-153
Life history and ancestry of the late Upper Palaeolithic infant from Grotta delle Mura, Italy

Here, the authors present paleogenomics, dental histology, geochemistry, radiocarbon dating, and bioarchaeological analysis of an Upper Palaeolithic infant from Grotta delle Mura (southern Italy). These data depict the health and development of the individual and point to regional population turnover at the time.

Owen Alexander Higgins
Alessandra Modi
David Caramelli
ResearchOpen Access20 Sept 2024
Nature Communications

Volume: 15, P: 1-16
Atomic structure of a nudivirus occlusion body protein determined from a 70-year-old crystal sample

Viral occlusion bodies are robust protein crystals that encapsulate virions of some insect viruses. Here, the authors determine the nudivirus occlusion body structure and describe common principles of occlusion body structure.

Jeremy R. Keown
Adam D. Crawshaw
Jonathan M. Grimes
ResearchOpen Access13 Jul 2023
Nature Communications

Volume: 14, P: 1-10
T-cell-derived helper factor allows in vivo induction of cytotoxic T cells in nu/nu mice

Hermann Wagner
Conny Hardt
Klaus Pfizenmaier
Research20 Mar 1980
Nature

Volume: 284, P: 278-280
Unlocking saponin biosynthesis in soapwort

Soapwort (Saponaria officinalis) is a rich reservoir of triterpenoid glycosides that often have important pharmaceutical, nutraceutical and agronomical potential. Here, the authors elucidate the complete biosynthetic pathway of saponarioside B, a major saponin constituent in soapwort.

Seohyun Jo
Amr El-Demerdash
Anne Osbourn
ResearchOpen Access23 Jul 2024
Nature Chemical Biology

Volume: 21, P: 215-226
Isolation of a human teratoma cell line which expresses F9 antigen

B. HOGAN
M. FELLOUS
P. AVNER
Research08 Dec 1977
Nature

Volume: 270, P: 515-518
Concept of Micro-environment related to the Regional Cytology of Lymph Nodes

D. W. MENZIES
Research18 Feb 1967
Nature

Volume: 213, P: 714-715
Predominantly female populations of an African butterfly

D F Owen
Research01 Aug 1966
Heredity

Volume: 21, P: 443-451
Tunnelling escape of waves

By considering waves from a bounding spherical volume, a clear onset of a tunnelling escape of waves that both defines a limiting number of well-coupled channels for any volume and explains the subsequent rapid fall-off of coupling strengths can be obtained.

David A. B. Miller
Zeyu Kuang
Owen D. Miller
ResearchOpen Access03 Dec 2024
Nature Photonics

Volume: 19, P: 284-290
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Incubation time for AIDS from French transfusion-associated cases

D. Costagliola
J-Y. Mary
A-J. Valleron
Research27 Apr 1989
Nature

Volume: 338, P: 768-769
Complete biosynthesis of the potent vaccine adjuvant QS-21

Vaccine immunoadjuvants are central to vaccine efficiency. Now, the complete characterization of the biosynthetic pathway of QS-21, a potent immunoadjuvant produced by the Chilean soapbark tree, has been reported. These findings open the door to heterologous production of QS-21 and new-to-nature adjuvants.

Laetitia B. B. Martin
Shingo Kikuchi
Anne Osbourn
ResearchOpen Access26 Jan 2024
Nature Chemical Biology

Volume: 20, P: 493-502
Binding of Concanavalin A to the Surface of Unfertilized and Fertilized Ascidian Eggs

A. MONROY
G. ORTOLANI
G. MILLONIG
Research06 Apr 1973
Nature

Volume: 242, P: 409-410
A New Synthesis of Vitamin A₂ : Conversion of Vitamin A₁ to A₂

R. K. BARUA
M. G. R. NAIR
Research13 Jan 1962
Nature

Volume: 193, P: 165
Intergalactic thermonuclear γ-ray line

DONALD D. CLAYTON
Research01 Feb 1985
Nature

Volume: 313, P: 534
Age of the New Red Sandstone in South Devonshire

D. J. C. LAMING
Research01 Aug 1965
Nature

Volume: 207, P: 624-625
Concentration dependence of currents through single sodium-selective pores in frog skin

W. Van Driessche
B. Lindemann
Research01 Nov 1979
Nature

Volume: 282, P: 519-520
Apostatic selection and population density

J J D Greenwood
Research01 Feb 1969
Heredity

Volume: 24, P: 157-161
Biochemical Consequences of Ethidium Bromide Treatment of Sea Urchin Embryos

VICTOR D. VACQUIER
J. RUSSELL CLAYBROOK
Research15 Nov 1969
Nature

Volume: 224, P: 706-707
Iron-coated Komodo dragon teeth and the complex dental enamel of carnivorous reptiles

Chemical and structural imaging of Komodo dragon teeth reveals that they maintain their sharp cutting edges through iron-enriched coatings, a unique adaptation compared with theropod dinosaurs (for which they have previously been used as an extant model).

Aaron R. H. LeBlanc
Alexander P. Morrell
Owen Addison
ResearchOpen Access24 Jul 2024
Nature Ecology & Evolution

Volume: 8, P: 1711-1722
Comparative cellular analysis of motor cortex in human, marmoset and mouse

An examination of motor cortex in humans, marmosets and mice reveals a generally conserved cellular makeup that is likely to extend to many mammalian species, but also differences in gene expression, DNA methylation and chromatin state that lead to species-dependent specializations.

Trygve E. Bakken
Nikolas L. Jorstad
Ed S. Lein
ResearchOpen Access06 Oct 2021
Nature

Volume: 598, P: 111-119
Broad fault zones enable deep fluid transport and limit earthquake magnitudes

Geophysical data from Chain Transform Fault reveal that broad damage zones preferentially facilitate fluid transport that cools the mantle, increasing earthquake depths. Fluids weaken the fault and segment it, limiting earthquake magnitudes.

Konstantinos Leptokaropoulos
Catherine A. Rychert
Satish C. Singh
ResearchOpen Access16 Sept 2023
Nature Communications

Volume: 14, P: 1-11
Genomic investigations of unexplained acute hepatitis in children

An investigation using various methods reports an association between adeno-associated virus 2 and paediatric hepatitis of unknown aetiology.

Sofia Morfopoulou
Sarah Buddle
Judith Breuer
ResearchOpen Access30 Mar 2023
Nature

Volume: 617, P: 564-573
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus

Serum urate concentration can be studied in large datasets to find genetic and epigenetic loci that may be related to cardiometabolic traits. Here the authors identify and replicate 100 urate-associated CpGs, which provide insights into urate GWAS loci and shared CpGs of urate and cardiometabolic traits.

Adrienne Tin
Pascal Schlosser
Anna Köttgen
ResearchOpen Access09 Dec 2021
Nature Communications

Volume: 12, P: 1-18
Tentative confirmation of an aurora on Uranus

John Caldwell
Richard Wagener
Th. Encrenaz
Research26 May 1983
Nature

Volume: 303, P: 310-312
Mating Preferences in Wild Birds

D. F. OWEN
Research01 Aug 1964
Nature

Volume: 203, P: 986
A framework for evaluating the performance of SMLM cluster analysis algorithms

This analysis compares the performance of seven algorithms for cluster analysis of single-molecule localization microscopy data. The results provide a framework for comparing these types of methods and point users to the best tools.

Daniel J. Nieves
Jeremy A. Pike
Dylan M. Owen
Research10 Feb 2023
Nature Methods

Volume: 20, P: 259-267
Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

The authors present the largest genome-wide association study to date for a rare Parkinsonian disorder, progressive supranuclear palsy (PSP). They include follow-up investigations of the identified susceptibility loci, functional consequences, and cell-specific pathologies, providing insights into genetic and molecular mechanisms underlying PSP.

Kurt Farrell
Jack Humphrey
Adam Naj
ResearchOpen Access09 Sept 2024
Nature Communications

Volume: 15, P: 1-17
Detection of TeV photons from the active galaxy Markarian 421

M. Punch
C. W. Akerlof
C. Wilson
Research06 Aug 1992
Nature

Volume: 358, P: 477-478
Experimental Model for von Willebrand's Disease

DOMINIQUE MEYER
C. S. P. JENKINS
MARIE-JOSÉ LARRIEU
Research01 Jun 1973
Nature

Volume: 243, P: 293-294
Dependence on Temperature of the Interlayer Spacing in Carbons of Different Graphitic Perfection

E. G. STEWARD
B. P. COOK
E. A. KELLETT
Research17 Sept 1960
Nature

Volume: 187, P: 1015-1016
Modeling human adaptive immune responses with tonsil organoids

An in vitro human tonsil tissue-based system captures key features of a functional germinal center and can be used to study humoral immune responses to vaccines, new antigens and adjuvants.

Lisa E. Wagar
Ameen Salahudeen
Mark M. Davis
Research11 Jan 2021
Nature Medicine

Volume: 27, P: 125-135
Distinct genetic liability profiles define clinically relevant patient strata across common diseases

Stratified medicine promises to tailor treatment for individual patients, however it remains a major challenge to leverage genetic risk data to aid patient stratification. Here the authors introduce an approach to stratify individuals based on the aggregated impact of their genetic risk factor profiles on tissue-specific gene expression levels, and highlight its ability to identify biologically meaningful and clinically actionable patient subgroups, supporting the notion of different patient ‘biotypes’ characterized by partially distinct disease mechanisms.

Lucia Trastulla
Georgii Dolgalev
Michael J. Ziller
ResearchOpen Access01 Jul 2024
Nature Communications

Volume: 15, P: 1-28
Adeno-associated virus 2 infection in children with non-A–E hepatitis

A case–control study investigating the causes of recent cases of acute hepatitis of unknown aetiology in 32 children identifies an association between adeno-associated virus infection and host genetics in disease susceptibility.

Antonia Ho
Richard Orton
Emma C. Thomson
Research30 Mar 2023
Nature

Volume: 617, P: 555-563

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