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Showing 1–50 of 108 results

Advanced filters: Author: D C Seldin Clear advanced filters

p53 deficiency and misexpression of protein kinase CK2α collaborate in the development of thymic lymphomas in mice

Esther Landesman-Bollag
Padma L Channavajhala
David C Seldin
Research16 Jun 1998
Oncogene

Volume: 16, P: 2965-2974
Charcot–Marie–Tooth neuropathy type 1B is associated with mutations of the myelin P₀ gene

Kiyoshi Hayasaka
Masato Himoro
Phillip F. Chance
Research01 Sept 1993
Nature Genetics

Volume: 5, P: 31-34
Protein kinase CK2 in mammary gland tumorigenesis

Esther Landesman-Bollag
Raphaëlle Romieu-Mourez
David C Seldin
Research22 Jun 2001
Oncogene

Volume: 20, P: 3247-3257
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

Michael Seldin and colleagues report a genome-wide association study and meta-analyses for primary biliary cirrhosis. They identify three loci newly associated with susceptibility to this autoimmune liver disease.

Xiangdong Liu
Pietro Invernizzi
Michael F Seldin
Research18 Jul 2010
Nature Genetics

Volume: 42, P: 658-660
Characterization of the myotonic dystrophy region predicts multiple protein isoform–encoding mRNAs

G. Jansen
M. Mahadevan
B. Wieringa
Research01 Jul 1992
Nature Genetics

Volume: 1, P: 261-266
Automated DNA sequencing and analysis of 106 kilobases from human chromosome 19q13.3

A. Martin-Gallardo
W. R. McCombie
J. C. Venter
Research01 Apr 1992
Nature Genetics

Volume: 1, P: 34-39
Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene

Qi Zhao
Richard R. Behringer
Benoit de Crombrugghe
Research01 Jul 1996
Nature Genetics

Volume: 13, P: 275-283
Mutations in TWIST, a basic helix–loop–helix transcription factor, in Saethre-Chotzen syndrome

Timothy D. Howard
William A. Paznekas
Ethylin Wang Jabs
Research01 Jan 1997
Nature Genetics

Volume: 15, P: 36-41
Increased AID results in mutations at the CRLF2 locus implicated in Latin American ALL health disparities

Rates of Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) continue to rise in Hispanics and Latinos. Authors developed a digital PCR assay to quantify activation-induced cytidine deaminase activity at risk loci involved in cancer etiology that may contribute to this health disparity.

Valeria Rangel
Jason N. Sterrenberg
Nicholas R. Pannunzio
ResearchOpen Access27 Jul 2024
Nature Communications

Volume: 15, P: 1-15
Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome

Elena V. Semina
Rebecca Reiter
Jeffrey C. Murray
Research01 Dec 1996
Nature Genetics

Volume: 14, P: 392-399
Reversal of Vitamin-D₂-Induced Hypercalciuria by Chlorothiazide

Uri Alon
Martha D Wellons
James C M Chan
Research01 Feb 1983
Pediatric Research

Volume: 17, P: 117-119
Endosomes from kidney collecting tubule cells contain the vasopressin-sensitive water channel

A. S. Verkman
Wayne I. Lencer
D. A. Ausiello
Research19 May 1988
Nature

Volume: 333, P: 268-269
Changes in Intracellular Hydrogen Ion Activity in Acute Experimental Salicylate Intoxication

J B Moon
D O'Brien
Research01 Jul 1967
Pediatric Research

Volume: 1, P: 277-286
Globozoospermia in mice lacking the casein kinase II α′ catalytic subunit

Xin Xu
Paul A. Toselli
David C. Seldin
Research01 Sept 1999
Nature Genetics

Volume: 23, P: 118-121
Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut

Systems genetics reveals interactions between host and microbial phenotypes in the murine gut, including a role for Akkermansia muciniphila in the production of immunomodulatory ornithine lipids.

Qijun Zhang
Vanessa Linke
Federico E. Rey
ResearchOpen Access09 Feb 2023
Nature Microbiology

Volume: 8, P: 424-440
Red Blood Cell Carbonic Anhydrase Activity in Children with Distal Renal Tubular Acidosis

B S Kaplan
M Mills
D Leblanc
Research01 Oct 1977
Pediatric Research

Volume: 11, P: 1039-1042
Protein kinase CKIIα interacts with the Bcr moiety of Bcr/Abl and mediates proliferation of Bcr/Abl-expressing cells

Suparna Mishra
Anja Reichert
John Groffen
Research13 Nov 2003
Oncogene

Volume: 22, P: 8255-8262
Allele-specific replication timing of imprinted gene regions

D. Kitsberg
S. Selig
H. Cedar
Research29 Jul 1993
Nature

Volume: 364, P: 459-463
Sex differences in heart mitochondria regulate diastolic dysfunction

In this paper, the authors show that sex differences in mitochondrial DNA levels and function in the heart contribute to sex biases in functions relevant to heart failure, identifying Acsl6 as a mitochondrial sex-biased regulator of diastolic function.

Yang Cao
Laurent Vergnes
Aldons J. Lusis
ResearchOpen Access04 Jul 2022
Nature Communications

Volume: 13, P: 1-14
Transancestral mapping and genetic load in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong ethnic and gender bias. In a transancestral genetic association study, Langefeldet al. identify 24 novel regions associated with risk to lupus and propose a cumulative hits hypothesis for loci conferring risk to SLE.

Carl D. Langefeld
Hannah C. Ainsworth
Timothy J. Vyse
ResearchOpen Access17 Jul 2017
Nature Communications

Volume: 8, P: 1-18
A mechanistic framework for cardiometabolic and coronary artery diseases

Koplev et al. apply interactive system analyses to infer and characterize gene-regulatory networks (GRNs) active within and across tissues that cause cardiometabolic disease and coronary artery disease (CAD). By including GWAS in the integrative analysis, the provided multiorgan framework of GRNs is suggested to explain significantly more heritability of CAD than what has been achieved by analyzing GWAS alone.

Simon Koplev
Marcus Seldin
Johan L. M. Björkegren
Research12 Jan 2022
Nature Cardiovascular Research

Volume: 1, P: 85-100
A new exon created by intronic insertion of a rearranged LINE-1 element as the cause of chronic granulomatous disease

Christof Meischl
Martin de Boer
Dirk Roos
Research31 Aug 2000
European Journal of Human Genetics

Volume: 8, P: 697-703
Maternal UPD 20 in a hyperactive child with severe growth retardation

I Chudoba
Y Franke
U Claussen
Research22 Jun 1999
European Journal of Human Genetics

Volume: 7, P: 533-540
Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

Lindsey Criswell and colleagues report an association between three independent variants near TNFAIP3 and systemic lupus erythematosus (SLE). In a related study, Patrick Gaffney and colleagues report results of a genome-wide association study for SLE, also identifying variants in the TNFAIP3 region on 6q23 that are strongly associated with the disease. The same region on 6q23 has recently been associated with rheumatoid arthritis, but only a subset of risk alleles in this region seem to be common to both diseases.

Stacy L Musone
Kimberly E Taylor
Lindsey A Criswell
Research01 Aug 2008
Nature Genetics

Volume: 40, P: 1062-1064
Activation of different Wnt/β-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors

Keiko Miyoshi
Andrea Rosner
Lothar Hennighausen
Research15 Aug 2002
Oncogene

Volume: 21, P: 5548-5556
Genetic analysis of multiplex rheumatoid arthritis families

D Bali
S Gourley
MF Seldin
Research29 Sept 1999
Genes & Immunity

Volume: 1, P: 28-36
JNK/SAPK activity contributes to TRAIL-induced apoptosis

Ingrid Herr
Dagmar Wilhelm
Klaus-Michael Debatin
Research28 Jan 1999
Cell Death & Differentiation

Volume: 6, P: 130-135
A genome-wide association study identifies six novel risk loci for primary biliary cholangitis

Primary biliary cholangitis is an autoimmune liver disease. Here, the authors show that variants in interleukin genes which potentially deregulate their expression are associated with this condition, and suggest that the IL21 signalling pathway may have a role in disease aetiology.

Fang Qiu
Ruqi Tang
Xiong Ma
ResearchOpen Access20 Apr 2017
Nature Communications

Volume: 8, P: 1-8
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Primary biliary cirrhosis is an autoimmune liver disease with poor therapeutic options. Here Cordell et al. a perform meta-analysis of European genome-wide association studies identifying six novel risk loci and a number of potential therapeutic pathways.

Heather J. Cordell
Younghun Han
Katherine A. Siminovitch
ResearchOpen Access22 Sept 2015
Nature Communications

Volume: 6, P: 1-11
The ever-expanding myokinome: discovery challenges and therapeutic implications

Myokines are emerging as potential mediators of some of the beneficial effects of exercise on the body. Here, Whitham and Febbraio discuss the challenges facing the discovery and validation of myokines and highlight selected myokines with the potential to be therapeutically exploited in cancer and metabolic disease.

Martin Whitham
Mark A. Febbraio
Reviews12 Sept 2016
Nature Reviews Drug Discovery

Volume: 15, P: 719-729
Molecular characterization of a novel amplicon at 1q21-q22 frequently observed in human sarcomas

A Forus
J-M Berner
O Myklebost
Research01 Aug 1998
British Journal of Cancer

Volume: 78, P: 495-503
Brain distribution of UCP2 mRNA: In situ hybridization histochemistry studies

D Richard
Q Huang
D Ricquier
Research13 Jul 1999
International Journal of Obesity

Volume: 23, P: S53-S55
The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis

WK Chung
A Luke
RL Leibel
Research13 Jul 1999
International Journal of Obesity

Volume: 23, P: S49-S50
A communal catalogue reveals Earth’s multiscale microbial diversity

As phase 1 of the Earth Microbiome Project, analysis of 16S ribosomal RNA sequences from more than 27,000 environmental samples delivers a global picture of the basic structure and drivers of microbial distribution.

Luke R. Thompson
Jon G. Sanders
Hongxia Zhao
ResearchOpen Access01 Nov 2017
Nature

Volume: 551, P: 457-463
Pseudohypoaldosteronism due to Sweat Gland Dysfunction

Sudhir K Anand
Linda Froberg
James C Wright
Research01 Jul 1976
Pediatric Research

Volume: 10, P: 677-682
Role of insulin resistance in the genesis of sodium sensitivity in essential hypertension

S Kuroda
T Uzu
G Kimura
Research24 Mar 1999
Journal of Human Hypertension

Volume: 13, P: 257-262
Partial rescue of the Na⁺-Ca²⁺ exchanger (NCX1) knock-out mouse by transgenic expression of NCX1

Chung-Hyun Cho
So-Young Lee
Chin O Lee
ResearchOpen Access01 Apr 2003
Experimental & Molecular Medicine

Volume: 35, P: 125-135
Imaging with prostate-specific membrane antigen (PSMA) in prostate cancer

MR Feneley
H Jan
KE Britton
Research10 May 2000
Prostate Cancer and Prostatic Diseases

Volume: 3, P: 47-52
Common variants at CD40 and other loci confer risk of rheumatoid arthritis

Robert Plenge and colleagues report the results of a meta-analysis of published genome-wide association studies that led to the identification of two previously unknown variants associated with rheumatoid arthritis.

Soumya Raychaudhuri
Elaine F Remmers
Robert M Plenge
Research14 Sept 2008
Nature Genetics

Volume: 40, P: 1216-1223
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

Eli Stahl and colleagues report results of a genome-wide association study meta-analysis and replication study for rheumatoid arthritis. Their work identifies several new risk loci and highlights genetic overlap with other autoimmune diseases.

Eli A Stahl
Soumya Raychaudhuri
Robert M Plenge
Research09 May 2010
Nature Genetics

Volume: 42, P: 508-514
HSPD1 is not a major susceptibility gene for rheumatoid arthritis in the French Caucasian population

Laurent Jacq
Vitor Hugo Teixeira
François Cornélis
Research11 Oct 2007
Journal of Human Genetics

Volume: 52, P: 1036-1039
Changes in muscle UCP3 expression and serum leptin in food restricted and refed rats

M Marzolo
C Pagano
G Federspil
Research24 Jul 2000
International Journal of Obesity

Volume: 24, P: S131-S133
Uncoupling protein-2 (UCP2): Molecular and genetic studies

D Ricquier
Research13 Jul 1999
International Journal of Obesity

Volume: 23, P: S38-S42
Study of the thrombopoietin receptor in essential thrombocythemia

JJ Kiladjian
N Elkassar
C Gardin
Research01 Nov 1997
Leukemia

Volume: 11, P: 1821-1826
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

Soumya Raychaudhuri and colleagues demonstrate the utility of GRAIL, a software program used to prioritize results from genome-wide association studies for further replication, applied here to rheumatoid arthritis. The authors seek replication of their predictions in additional independent cohorts and report three new genetic loci associated with RA susceptibility.

Soumya Raychaudhuri
Brian P Thomson
Robert M Plenge
Research08 Nov 2009
Nature Genetics

Volume: 41, P: 1313-1318
Cloning and mRNA tissue distribution of human PPARγ coactivator-1

D Larrouy
H Vidal
D Langin
Research13 Jan 2000
International Journal of Obesity

Volume: 23, P: 1327-1332
Uncoupling protein-2 (UCP2) and uncoupling protein-3 (UCP3) expression in adipose tissue and skeletal muscle in humans

D Langin
D Larrouy
H Vidal
Research13 Jul 1999
International Journal of Obesity

Volume: 23, P: S64-S67
Collagen type XVIII/endostatin is differentially expressed in primary and metastatic colorectal cancers and ovarian carcinomas

U Guenther
H Herbst
D Schuppan
ResearchOpen Access13 Nov 2001
British Journal of Cancer

Volume: 85, P: 1540-1545
Rat uncoupling protein 2 (UCP2): Expression in obese ventromedial hypothalamus (VMH)-lesioned animals

A Strobel
M Combettes-Souverain
T Issad
Research29 Oct 1998
International Journal of Obesity

Volume: 22, P: 1121-1126
Preferential loss of a polymorphic RIZ allele in human hepatocellular carcinoma

W Fang
Z Piao
S Huang
ResearchOpen Access20 Mar 2001
British Journal of Cancer

Volume: 84, P: 743-747

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