Whether mRNA SARS-CoV-2 vaccines promote T cells within the nasal mucosa of vaccine recipients is not known. Here the authors show that after mRNA SARS-CoV-2 vaccination, antigen specific T cells can be measured in the nasal mucosa and that these T cells may be localised to respond to a subsequent virus infection.
Clinical trial registration NCT04713163
- Aloysious Ssemaganda
- Huong Mai Nguyen
- Lyle R. McKinnon
