Nature Search

The poetical chemist

D. G. KING-HELE
Books & Arts17 May 1974
Nature

Volume: 249, P: 291-292
Spatial genomic heterogeneity within localized, multifocal prostate cancer

Paul Boutros, Robert Bristow and colleagues report a molecular analysis of the spatial heterogeneity of clinically localized, multifocal prostate cancer. They find that multifocal tumors are highly heterogeneous, and they identify a novel recurrent amplification of MYCL1.

Paul C Boutros
Michael Fraser
Robert G Bristow
Research25 May 2015
Nature Genetics

Volume: 47, P: 736-745
A narrow window of cortical tension guides asymmetric spindle positioning in the mouse oocyte

Asymmetric spindle positioning in female mouse meiosis depends on the assembly of actin networks. Here, Chaigne et al. show by theoretical modelling and artificial manipulation of the oocyte cortex that a narrow stiffness regime is required to correctly position the spindle during meiosis I in the mouse oocyte.

A. Chaigne
C. Campillo
M. E. Terret
Research19 Jan 2015
Nature Communications

Volume: 6, P: 1-10
The status of earthquake prediction

David D. Jackson
Comments & Opinion18 Mar 1999
Nature

P: 1-3
The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

Hans-Peter Klenk
Rebecca A. Clayton
J. Craig Venter
Research27 Nov 1997
Nature

Volume: 390, P: 364-370
Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium

Fungi from the genus Fusarium are important pathogens of animals and crop plants. Some have a wide host range, whereas others are more specific in the organisms they infect. Here, clues are provided as to how differences in specificity come about. The genomes of two Fusarium fungi with differing host ranges have been sequenced, and compared with the genome of a third species. Experiments show that transferring two whole chromosomes turns a non-pathogenic Fusarium strain into a pathogenic one.

Li-Jun Ma
H. Charlotte van der Does
Martijn Rep
ResearchOpen Access18 Mar 2010
Nature

Volume: 464, P: 367-373
Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis

Endophilin-A2 (endoA2) is shown to mediate clathrin-independent endocytosis of Shiga and cholera toxins, and to function in parallel with dynamin and actin in the pulling-force-driven scission of Shiga-toxin-induced tubular structures.

Henri-François Renard
Mijo Simunovic
Ludger Johannes
Research17 Dec 2014
Nature

Volume: 517, P: 493-496
The Effects Upon Haemopoiesis of Prolonged Intra-arterial Infusions of Methotrexate Combined with the Intermittent Administration of Folinic Acid

D P Rose
M R Bond
Christine Evans
Research01 Mar 1965
British Journal of Cancer

Volume: 19, P: 126-133
The other carbon cycle

D. H. Green
S. M. Eggins
G. Yaxley
News & Views16 Sept 1993
Nature

Volume: 365, P: 210-211
Comparison of the solution structures of microcystin-LR and motuporin

A comparison of the structures of two cyanobacterial toxins yields insights into how they may inhibit protein phosphatase-1 and -2A and why microcystins but not motuporin may covalently modify their protein phosphatase targets.

John R. Bagu
Frank D. Sönnichsen
Charles F.B. Holmes
Correspondence01 Feb 1995
Nature Structural Biology

Volume: 2, P: 114-116
Controlling a spillover pathway with the molecular cork effect

Spillover of reactants from one active site to another is important in heterogeneous catalysis but is notoriously hard to detect or control, especially for hydrogen. The hydrogen spillover pathway on a Pd–Cu alloy can now be controlled by reversible adsorption of a spectator molecule. This effect observed during a surface catalysed reaction should prove useful for controlling uptake and release of hydrogen in a model storage system.

Matthew D. Marcinkowski
April D. Jewell
E. Charles H. Sykes
Research21 Apr 2013
Nature Materials

Volume: 12, P: 523-528
Clinical and radiographic features of multiple epiphyseal dysplasia not linked to the COMP or type IX collagen genes

Geert R Mortier
Kathryn Chapman
Michael D Briggs
Research30 Aug 2001
European Journal of Human Genetics

Volume: 9, P: 606-612
Erratum: The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

Hans-Peter Klenk
Rebecca A. Clayton
J. Craig Venter
Amendments and CorrectionsOpen Access01 Jul 1998
Nature

Volume: 394, P: 101
Equilibrium physics breakdown reveals the active nature of red blood cell flickering

The membranes of red blood cells exhibit a flickering motion that has long been ascribed a thermal origin. Microrheology experiments provide direct evidence that flickering is an active process characterized by non-equilibrium dynamics.

H. Turlier
D. A. Fedosov
T. Betz
Research18 Jan 2016
Nature Physics

Volume: 12, P: 513-519
Transient lensing from a photoemitted electron gas imaged by ultrafast electron microscopy

Excited charge carriers, such as photoelectrons, play an important role in fundamental and technological fields. Here the authors employ an ultrafast electron microscope to directly visualize the cyclotron oscillations and oblate-to-prolate shape change of a photoemitted electron gas from a laser-excited copper surface.

Omid Zandi
Allan E. Sykes
Renske M. van der Veen
ResearchOpen Access12 Jun 2020
Nature Communications

Volume: 11, P: 1-11
External forces control mitotic spindle positioning

The cell division axis is determined by the position of the mitotic spindle. How geometrical cues influence spindle orientation is analysed in cells cultured on micropatterns. These experiments show that the mitotic spindle rotates to align with the forces produced by retraction fibres and suggest that forces may be transmitted through a sub-cortical actin structure.

Jenny Fink
Nicolas Carpi
Matthieu Piel
Research12 Jun 2011
Nature Cell Biology

Volume: 13, P: 771-778
Mechanism of hard-nanomaterial clearance by the liver

The blood clearance mechanism, by the liver, of administered hard nanomaterials is reported in relation to blood flow dynamics, organ microarchitecture and cellular phenotype.

Kim M. Tsoi
Sonya A. MacParland
Warren C. W. Chan
Research15 Aug 2016
Nature Materials

Volume: 15, P: 1212-1221
β-Helix structure and ice-binding properties of a hyperactive antifreeze protein from an insect

Steffen P. Graether
Michael J. Kuiper
Peter L. Davies
Research20 Jul 2000
Nature

Volume: 406, P: 325-328
Targeting the sarcomere to correct muscle function

The balance between muscle contraction and relaxation is disrupted in various human diseases, including heart failure, cardiomyopathies, skeletal myopathies and neuromuscular conditions. Here, Hwang and Sykes discuss therapeutic strategies aimed at modulating the mechanical function of the sarcomere, focusing on agents that affect the function of myosin or the troponin complex.

Peter M. Hwang
Brian D. Sykes
Reviews17 Apr 2015
Nature Reviews Drug Discovery

Volume: 14, P: 313-328
Detection of minimal disease using rearranged immunoglobulin heavy chain genes from intermediate- and high-grade malignant B cell non-Hodgkin’s lymphoma

N van Belzen
PE Hupkes
MB van’t Veer
Research01 Oct 1997
Leukemia

Volume: 11, P: 1742-1752
Successes And Failures

D. V. LINDLEY
Books & Arts25 Jul 1970
Nature

Volume: 227, P: 419
Structure of the carboxy-terminal domain of bovine rhodopsin

The biologically active carboxy-terminal peptide of the G-protein receptor, rhodopsin, forms a compact structure, suggesting that it is a structural domain in this integral membrane protein. The disposition of serines explains receptor kinase specificity.

Philip L. Yeagle
James L. Alderfer
Arlene D. Albert
Correspondence01 Oct 1995
Nature Structural Biology

Volume: 2, P: 832-834
Ultrastructural findings in solar retinopathy

M W Hope-Ross
G J Mahon
D B Archer
Research01 Jan 1993
Eye

Volume: 7, P: 29-33
A soft cortex is essential for asymmetric spindle positioning in mouse oocytes

Verlhac, Terret and colleagues report that softening of the mouse oocyte cortex during meiosis I is needed for spindle migration and positioning. They show that Mos/mAPK signalling triggers myosin II exclusion from the cortex and an Arp2/3-dependent cortical F-actin thickening that contributes to cortical softening.

Agathe Chaigne
Clément Campillo
Marie-Emilie Terret
Research14 Jul 2013
Nature Cell Biology

Volume: 15, P: 958-966
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

The authors uncover a new role for the RNA-binding protein Msi2 in the regulation of hematopoietic stem cell homeostasis and leukemogenesis. Msi2 is required for the maintenance of the balance between progenitor renewal and differentiation, and its overexpression cooperates with oncogenic events to induce aggressive leukemia. Msi2 expression is also elevated in human myeloid leukemias and may be a new prognostic marker and therapeutic target in acute myeloid leukemia.

Michael G Kharas
Christopher J Lengner
George Q Daley
Research08 Jul 2010
Nature Medicine

Volume: 16, P: 903-908
The Rothamsted Field Experiments on the Growth of Wheat

R. D. PRESTON
News10 May 1941
Nature

Volume: 147, P: 583-584
Proteins as machines

Thomas D. Pollard
News & Views02 Jan 1992
Nature

Volume: 355, P: 17-18
Orbit Theory

D. G. KING-HELE
Books & Arts24 Sept 1966
Nature

Volume: 211, P: 1343
Descriptive Geology

D. T. DONOVAN
Books & Arts12 Jul 1969
Nature

Volume: 223, P: 219-220
Artificially decreasing cortical tension generates aneuploidy in mouse oocytes

The developmental potential of human and murine oocytes is predicted by their mechanical properties. Here the authors show that artificial reduction of cortex tension produces aneuploid mouse oocytes and speculate that this may contribute to the high aneuploidy rate typical of female meiosis.

Isma Bennabi
Flora Crozet
Marie-Emilie Terret
ResearchOpen Access03 Apr 2020
Nature Communications

Volume: 11, P: 1-14
The Dynamical Theory of Gases

C. G. D.
Books & Arts25 Aug 1921
Nature

Volume: 107, P: 804-805
Mapping autism risk loci using genetic linkage and chromosomal rearrangements

Peter Szatmari
Andrew D Paterson
Andy Shih
Research18 Feb 2007
Nature Genetics

Volume: 39, P: 319-328
Predictors of circuit health in neonatal patients receiving extracorporeal membrane oxygenation (ECMO)

Rita G. Hazboun
Nada Darwish
Karen D. Hendricks-Muñoz
ResearchOpen Access24 Jan 2022
Scientific Reports

Volume: 12, P: 1-6
An investigation into the relative efficiency of dextro-rotating and laevo-rotating spiral paste fillers in the southern hemisphere

P Sykes
D G Sykes
Research08 Apr 1995
British Dental Journal

Volume: 178, P: 259-262
Sexual dimorphism and the evolution of higher primates

R. D. Martin
News & Views01 Sept 1980
Nature

Volume: 287, P: 273-274
Therapy of Acute Leukaemia

J M Bridges
D M Hayes
M G Nelson
Research01 Mar 1962
British Journal of Cancer

Volume: 16, P: 46-55
Xenotransplantation: current status and a perspective on the future

Could xenotransplantation using pigs as the transplant source solve the severe shortage of human organ donors? This Review describes the recent advances that are helping to bring this approach closer to the clinic and the obstacles that still need to be overcome.

Yong-Guang Yang
Megan Sykes
Reviews01 Jul 2007
Nature Reviews Immunology

Volume: 7, P: 519-531
Recovery of cell subpopulations from human tumour xenografts following dissociation with different enzymes

M J Allalunis-Turner
D W Siemann
Research01 Oct 1987
British Journal of Cancer

Volume: 54, P: 615-622
Donor-specific B-cell tolerance after ABO-incompatible infant heart transplantation

Xiaohu Fan
Andrew Ang
Lori J West
Research24 Oct 2004
Nature Medicine

Volume: 10, P: 1227-1233
Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival

Transcription factors compete for superenhancer sites and have antagonist functions. Farrar and colleagues identify regulatory competition between STAT5 and IKAROS or NF-κB in B cells and show that the ratio of STAT5 to IKAROS or to NF-κB can serve as a prognostic marker of disease severity of the leukemia B-ALL.

Casey D S Katerndahl
Lynn M Heltemes-Harris
Michael A Farrar
Research03 Apr 2017
Nature Immunology

Volume: 18, P: 694-704
MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration

MHC-I is expressed in neurons where it is implicated in synaptic plasticity and neuron regeneration. Here, Cebrián et al. report an increase in MHC-I expression in brain neurons from Parkinson’s disease patients, which is triggered by microglial activation and circulating dopamine.

Carolina Cebrián
Fabio A. Zucca
David Sulzer
Research16 Apr 2014
Nature Communications

Volume: 5, P: 1-14
Solution structure of the N-terminal domain of the δ subunit of the E. coli ATPsynthase

NMR studies of the δ subunit of the Escherichia coli F₁F₀-ATPsynthase reveal that it consists of an N-terminal six α-helix bundle and a less well ordered C terminus. Both domains are part of one of two separate connections between F₁ and F₀.

Stephan Wilkens
Stanley D. Dunn
Roderick A. Capaldi
Correspondence01 Mar 1997
Nature Structural Biology

Volume: 4, P: 198-201
Low-temperature, high-performance solution-processed metal oxide thin-film transistors formed by a ‘sol–gel on chip’ process

A low-temperature, solution-based preparation of amorphous, metal oxide semiconducting thin-films is reported. This ‘sol–gel on chip’ hydrolysis approach yields thin-film transistors with high field-effect mobilities, reproducible and stable turn-on voltages and high operational stability.

K. K. Banger
Y. Yamashita
H. Sirringhaus
Research12 Dec 2010
Nature Materials

Volume: 10, P: 45-50
Requirement for LIM kinases in acute myeloid leukemia

Patrizia Jensen
Michela Carlet
Stefan Fröhling
Research26 Jun 2020
Leukemia

Volume: 34, P: 3173-3185
Clonal stability in children with acute lymphoblastic leukemia (ALL) who relapsed five or more years after diagnosis

L Lo Nigro
G Cazzaniga
A Biondi
Research05 Feb 1999
Leukemia

Volume: 13, P: 190-195
Author Correction: Mast cells increase adult neural precursor proliferation and differentiation but this potential is not realized in vivo under physiological conditions

Joanna M. Wasielewska
Lisa Grönnert
Tara L. Walker
Amendments and CorrectionsOpen Access09 Nov 2020
Scientific Reports

Volume: 10, P: 1
BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas

Alejandro Ibáñez-Costa
Laura M. López-Sánchez
Raúl M. Luque
ResearchOpen Access09 Feb 2017
Scientific Reports

Volume: 7, P: 1-14
The ultimate database to (re)set the evolutionary history of primate genital bones

Federica Spani
Maria Pia Morigi
Monica Carosi
ResearchOpen Access27 May 2021
Scientific Reports

Volume: 11, P: 1-15
Humanized immune system mouse models: progress, challenges and opportunities

On 18 December 2018, the National Institute of Allergy and Infectious Diseases convened a workshop entitled ‘Recent Advances and Opportunities in the Development and Use of Humanized Immune System Mouse Models’.

Todd M. Allen
Michael A. Brehm
Mercy PrabhuDas
Comments & Opinion03 Jun 2019
Nature Immunology

Volume: 20, P: 770-774
First results from five multidisciplinary diagnostic centre (MDC) projects for non-specific but concerning symptoms, possibly indicative of cancer

D. Chapman
V. Poirier
Brian Nicholson
ResearchOpen Access06 Jul 2020
British Journal of Cancer

Volume: 123, P: 722-729

Search

Filter By:

Search

Quick links