Fan et al. analyze DNAm-derived leukocyte composition ratios (LCRs) in a large cohort with 17 years follow-up, assessing their associations with all-cause, cancer-specific, and lung-cancer-specific mortality. Several LCRs show strong, consistent associations, highlighting their value in long-term cancer mortality risk assessment exceeding a decade.
- Ziwen Fan
- Dominic Edelmann
- Hermann Brenner
