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Oncogene (32)
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Showing 1–50 of 65 results

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Publisher Correction: Advancing single-cell omics and cell-based therapeutics with quantum computing

Aritra Bose
Kahn Rhrissorrakrai
Jeannette M. Garcia
Amendments and Corrections03 Feb 2026
Nature Reviews Molecular Cell Biology

P: 1
Methyl group as a probe of chirality in Raman optical activity

D. Barron
Research05 Jun 1975
Nature

Volume: 255, P: 458-460
MiR-27b targets PPARγ to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells

J-J Lee
A Drakaki
K Struhl
Research28 Nov 2011
Oncogene

Volume: 31, P: 3818-3825
Expression of an antigen homologous to the human CO17-1A/GA733 colon cancer antigen in animal tissues

J Zaloudik
S Basak
D Herlyn
Research01 Oct 1997
British Journal of Cancer

Volume: 76, P: 909-916
An estimate of the fine structure constant

S. L. Glashow
D. V. Nanopoulos
Research11 Oct 1979
Nature

Volume: 281, P: 464-465
Direct observation of the structure of a metallic alloy glass

P.H. Gaskell
David J. Smith
J. R. A. Cleaver
Research11 Oct 1979
Nature

Volume: 281, P: 465-467
Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through Hypoxia-inducible factor

Masaya Baba
Syuiohi Hirai
Shigeo Ohno
Research09 May 2003
Oncogene

Volume: 22, P: 2728-2738
Macro view of microRNA function in osteoarthritis

MicroRNAs (miRNAs) function in several chronic diseases—miRNA-mediated fine control of genetic networks involved in tissue development and homeostasis becomes disrupted. Participating in production and maintenance of articular chondrocytes and skeletogenesis, miRNA are increasingly implicated in the pathogenesis of osteoarthritis. Data from animal and cell studies are discussed in this Review, alongside the potential for targeting miRNA in the clinic.

Shigeru Miyaki
Hiroshi Asahara
Reviews14 Aug 2012
Nature Reviews Rheumatology

Volume: 8, P: 543-552
Tumor suppressor protein VHL is induced at high cell density and mediates contact inhibition of cell growth

Masaya Baba
Syu-ichi Hirai
Shigeo Ohno
Research17 May 2001
Oncogene

Volume: 20, P: 2727-2736
Up-regulation of hypoxia-inducible factors HIF-1α and HIF-2α under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function

Marion Krieg
Richard Haas
Karl H Plate
Research16 Nov 2000
Oncogene

Volume: 19, P: 5435-5443
The von Hippel-Lindau tumor suppressor gene protects cells from UV-mediated apoptosis

Alan R Schoenfeld
Tchaiko Parris
Robert D Burk
Research30 Nov 2000
Oncogene

Volume: 19, P: 5851-5857
Advancing single-cell omics and cell-based therapeutics with quantum computing

Classical computing has inherent limitations in capturing cellular dynamics. This Roadmap article discusses how recent advancements in quantum computing could overcome bottlenecks in spatiotemporal single-cell omics analyses and how it may be integrated into cell-based therapeutics.

Aritra Bose
Kahn Rhrissorrakrai
Jeannette M. Garcia
Reviews02 Jan 2026
Nature Reviews Molecular Cell Biology

P: 1-15
Unraveling the functional dark matter through global metagenomics

A computational approach to generate reference-free protein families from the sequence space in metagenomes reveals an enormously diverse functional space.

Georgios A. Pavlopoulos
Fotis A. Baltoumas
Nikos C. Kyrpides
ResearchOpen Access11 Oct 2023
Nature

Volume: 622, P: 594-602
von Hippel–Lindau protein complex is regulated by cell density

Sankar Mohan
Robert D Burk
Research14 Aug 2003
Oncogene

Volume: 22, P: 5270-5280
Vascular endothelial growth factor expression is independent of hypoxia in human malignant glioma spheroids and tumours

M B Parliament
M J Allalunis-Turner
B Wolokoff
ResearchOpen Access07 Jan 2000
British Journal of Cancer

Volume: 82, P: 635-641
Correction: Corrigendum: Induction of interleukin-8 preserves the angiogenic response in HIF-1α–deficient colon cancer cells

Y Mizukami
W-S Jo
D C Chung
Amendments and Corrections01 Feb 2006
Nature Medicine

Volume: 12, P: 253
Trastuzumab resistance induces EMT to transform HER2⁺ PTEN⁻ to a triple negative breast cancer that requires unique treatment options

Joseph P. Burnett
Hasan Korkaya
Duxin Sun
ResearchOpen Access02 Nov 2015
Scientific Reports

Volume: 5, P: 1-13
RNAi modulation of placental sFLT1 for the treatment of preeclampsia

Preeclampsia, a hypertension condition with no approved therapies, is treated in monkeys by gene silencing in the placenta.

Anton A Turanov
Agnes Lo
Anastasia Khvorova
Research19 Nov 2018
Nature Biotechnology

Volume: 36, P: 1164-1173
Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein

Folliculin is a known tumour suppressor but the molecular mechanisms behind this function are unclear. Here the authors show that Folliculin regulates EGFR signalling by modulating its Rab7a-dependent trafficking.

Laura A. Laviolette
Julien Mermoud
Othon Iliopoulos
ResearchOpen Access28 Jun 2017
Nature Communications

Volume: 8, P: 1-14
The effect Akt2 deletion on tumor development in Pten^+/− mice

P-Z Xu
M-L Chen
N Hay
ResearchOpen Access11 Jul 2011
Oncogene

Volume: 31, P: 518-526
Blood and lymphatic systems are segregated by the FLCN tumor suppressor

Blood and lymphatic vessels bear a strong resemblance but do not share a lumen, thus maintaining their distinct functions. Here, the authors describe that Folliculin, a tumor suppressor, prevents the fusion of these vessels during development by limiting the plasticity of venous and lymphatic endothelial cells.

Ikue Tai-Nagara
Yukiko Hasumi
Yoshiaki Kubota
ResearchOpen Access09 Dec 2020
Nature Communications

Volume: 11, P: 1-12
Retinol semisolid preparations in cosmetics: transcutaneous permeation mechanism and behaviour

Yuan Wang
Qirong Zhang
Qi Xiang
ResearchOpen Access01 Oct 2024
Scientific Reports

Volume: 14, P: 1-11
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

This study finds that triple-negative breast cancers (TNBC) show an increased basal level of endoplasmic reticulum stress and activation of the XBP1 branch of the unfolded protein response; furthermore, XBP1 promotes tumour formation of TNBC cell lines by interacting with and regulating HIF1α.

Xi Chen
Dimitrios Iliopoulos
Laurie H. Glimcher
Research23 Mar 2014
Nature

Volume: 508, P: 103-107
Hypoxia and cell cycle regulation of the von Hippel–Lindau tumor suppressor

W Liu
H Xin
J R Gnarra
Research30 Aug 2010
Oncogene

Volume: 30, P: 21-31
MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways

I Keklikoglou
C Koerner
U Tschulena
ResearchOpen Access12 Dec 2011
Oncogene

Volume: 31, P: 4150-4163
Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells

D Kong
Y-S Piao
M Oshima
Research05 Dec 2011
Oncogene

Volume: 31, P: 3949-3960
SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative breast cancer model

G Kim
M Ouzounova
H Korkaya
Research17 Feb 2014
Oncogene

Volume: 34, P: 671-680
Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model

Laura Belloni
Silvia Di Cocco
Natalia Pediconi
ResearchOpen Access11 Sept 2018
Scientific Reports

Volume: 8, P: 1-12
Inhibition of the Wnt/β-catenin pathway by the WWOX tumor suppressor protein

N Bouteille
K Driouch
F Lallemand
Research25 May 2009
Oncogene

Volume: 28, P: 2569-2580
Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential

S Semba
F Trapasso
K Huebner
Research16 Jan 2006
Oncogene

Volume: 25, P: 2860-2872
Genomics and natural language processing

Mark D. Yandell
William H. Majoros
Reviews01 Aug 2002
Nature Reviews Genetics

Volume: 3, P: 601-610
A proteomic analysis reveals the loss of expression of the cell death regulatory gene GRIM-19 in human renal cell carcinomas

I Alchanati
S C Nallar
D V Kalvakolanu
Research29 May 2006
Oncogene

Volume: 25, P: 7138-7147
The von Hippel–Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C

X Niu
T Zhang
H Yang
Research04 Jul 2011
Oncogene

Volume: 31, P: 776-786
miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis

R I McCormick
C Blick
A L Harris
ResearchOpen Access28 Feb 2013
British Journal of Cancer

Volume: 108, P: 1133-1142
Binding and modulation of p53 by p300/CBP coactivators

Nancy L. Lill
Steven R. Grossman
David M. Livingston
Research19 Jun 1997
Nature

Volume: 387, P: 823-827
Tracheal development and the von Hippel–Lindau tumor suppressor homolog in Drosophila

Boris Adryan
Hans-Jochen H Decker
Tien Hsu
Research01 Jun 2000
Oncogene

Volume: 19, P: 2803-2811
Environmental triggers in IBD: a review of progress and evidence

A wide variety of environmental triggers have been associated with IBD pathogenesis, including the gut microbiota, diet, pollution and early-life factors. This Review discusses the latest evidence and progress towards better understanding the environmental factors associated with IBD.

Ashwin N. Ananthakrishnan
Charles N. Bernstein
Claudio Fiocchi
Reviews11 Oct 2017
Nature Reviews Gastroenterology & Hepatology

Volume: 15, P: 39-49
Redirected cellular cytotoxicity by infection of effector cells with a recombinant vaccinia virus encoding a tumor-specific monoclonal antibody

Stéphane Paul
Nadine Bizouarne
Marie Paule Kieny
Research15 Jun 2000
Cancer Gene Therapy

Volume: 7, P: 615-623
RETRACTED ARTICLE: miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer

J Zhang
Z Xiao
J Wang
ResearchOpen Access07 Jun 2012
British Journal of Cancer

Volume: 107, P: 352-359
Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential

J M Heddleston
Q Wu
J N Rich
Research12 Aug 2011
Cell Death & Differentiation

Volume: 19, P: 428-439
The IBD interactome: an integrated view of aetiology, pathogenesis and therapy

IBD is a complex disease characterized by multiple interacting pathogenic components. In this Perspectives, the authors advocate studying the 'IBD interactome' to build a molecular network of IBD, and discuss new concepts and tools to implement an unbiased systems approach that could facilitate development of novel therapies.

Heitor S. P. de Souza
Claudio Fiocchi
Dimitrios Iliopoulos
Reviews23 Aug 2017
Nature Reviews Gastroenterology & Hepatology

Volume: 14, P: 739-749
MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways

C Oneyama
J Ikeda
M Okada
Research07 Mar 2011
Oncogene

Volume: 30, P: 3489-3501
Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma

D Mahalingam
C M Espitia
S T Nawrocki
ResearchOpen Access20 Oct 2011
British Journal of Cancer

Volume: 105, P: 1563-1573
MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression

C Oneyama
E Morii
M Okada
Research22 Aug 2011
Oncogene

Volume: 31, P: 1623-1635
Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation of the PTEN–AKT pathway

T Palumbo
F R Faucz
C A Stratakis
Research21 May 2012
Oncogene

Volume: 32, P: 1651-1659
Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer

M Musumeci
V Coppola
D Bonci
Research02 May 2011
Oncogene

Volume: 30, P: 4231-4242
RKTG inhibits angiogenesis by suppressing MAPK-mediated autocrine VEGF signaling and is downregulated in clear-cell renal cell carcinoma

Y Zhang
X Jiang
Y Chen
Research05 Jul 2010
Oncogene

Volume: 29, P: 5404-5415
Fre2, a proviral integration site of Friend murine leukemia virus that is closely linked to Fv2

RW Friedrich
M Veit
CA Kozak
Reviews01 May 1997
Leukemia

Volume: 11, P: 619-623
Targeting KRas-dependent tumour growth, circulating tumour cells and metastasis in vivo by clinically significant miR-193a-3p

E G Seviour
V Sehgal
P T Ram
Research26 Sept 2016
Oncogene

Volume: 36, P: 1339-1350
Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α

A Soeda
M Park
D M Park
Research31 Aug 2009
Oncogene

Volume: 28, P: 3949-3959

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