The syndecan binding protein syntenin promotes the budding of intraluminal vesicles from the endosomal membrane, resulting in increased exosome secretion. Ghossoub et al.show that syntenin activates a pathway including ADP-ribsoylation factor 6 and phospholipase D to stimulate budding.
- Rania Ghossoub
- Frédérique Lembo
- Pascale Zimmermann
