Nature Search

Complete biosynthesis of QS-21 in engineered yeast

QS-21—an FDA-approved vaccine adjuvant—and several structural analogues of QS-21 can be synthesized in engineered yeast strains, and this process is much less laborious compared with the conventional mode of extraction from the Chilean soapbark tree.

Yuzhong Liu
Xixi Zhao
Jay D. Keasling
ResearchOpen Access08 May 2024
Nature

Volume: 629, P: 937-944
Three-dimensional structure of a tubulin-motor-protein complex

Andreas Hoenger
Elena P. Sablin
Ronald A. Milligan
Research20 Jul 1995
Nature

Volume: 376, P: 271-274
Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice

Individuals with SYK gain-of-function variants develop immunodeficiency and systemic inflammation, which are recapitulated in a knock-in mouse model. Treatment of these mice with bone marrow transplantation or with a SYK inhibitor ameliorates disease symptoms, highlighting potential therapeutic strategies for patients with SYK mutations.

Lin Wang
Dominik Aschenbrenner
Aleixo M. Muise
Research29 Mar 2021
Nature Genetics

Volume: 53, P: 500-510
Turbulent heating in galaxy clusters brightest in X-rays

Analysis of X-ray data of galaxy clusters shows that turbulent heating of the intracluster medium is sufficient to counteract the radiative energy losses from the medium.

I. Zhuravleva
E. Churazov
N. Werner
Research26 Oct 2014
Nature

Volume: 515, P: 85-87
Spectrum of Doubly Ionised Krypton

D. P. ACHARYA
Research16 Feb 1929
Nature

Volume: 123, P: 244
Effects of biochar amendment at various soil depths on maize roots and growth indices

S. Gaurav
B. Diptanu
Vishnu D. Rajput
ResearchOpen Access20 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Analysis of clinically relevant variants from ancestrally diverse Asian genomes

Clinically significant genetic variation in Asian populations is under-characterized. Here, the authors show the diversity in prevalence and spectrum of human disease and pharmacogenetic variants in a multi-ethnic Asian population.

Sock Hoai Chan
Yasmin Bylstra
Weng Khong Lim
ResearchOpen Access05 Nov 2022
Nature Communications

Volume: 13, P: 1-15
Early attention-deficit/hyperactivity disorder (ADHD) with NeuroDCT-ICA and rhinofish optimization (RFO) algorithm based optimized ADHD-AttentionNet

Ahmed Alhussen
Ahmed Ibrahim Alutaibi
Ghanshyam G. Tejani
ResearchOpen Access26 Feb 2025
Scientific Reports

Volume: 15, P: 1-20
The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus

D. P. Barlow
R. Stöger
N. Schweifer
Research03 Jan 1991
Nature

Volume: 349, P: 84-87
A WC/WO star exploding within an expanding carbon–oxygen–neon nebula

Observations of the supernova SN 2019hgp, identified about a day after its explosion, show that it occurred within a nebula of carbon, oxygen and neon, and was probably the explosion of a massive WC/WO star.

A. Gal-Yam
R. Bruch
N. Knezevic
Research12 Jan 2022
Nature

Volume: 601, P: 201-204
Super-cooled Water

LEONARD HAWKES
Research16 Feb 1929
Nature

Volume: 123, P: 244
The Birth of a Relativistic Jet Following the Disruption of a Star by a Cosmological Black Hole

By modelling the radio, optical, UV and X-ray data of the unusually bright cosmological explosion AT 2022cmc, Pasham et al. argue for the presence of a highly collimated jet moving at ≳99.99% the speed of light.

Dheeraj R. Pasham
Matteo Lucchini
Sheng Yang
Research30 Nov 2022
Nature Astronomy

Volume: 7, P: 88-104
Influence of Decompression Procedure on Heart Viability after Long-term Storage using Hyperbaric Oxygen and Hypothermia

BUI-MONG-HUNG
M. VIGANO
D. LAURENT
Research14 Sept 1968
Nature

Volume: 219, P: 1175-1177
NGC5128—a galaxy with a recently formed disk

Michel Marcelin
Jacques Boulesteix
Bruno Milliard
Research06 May 1982
Nature

Volume: 297, P: 38-42
Activity in primate visual cortex is minimally driven by spontaneous movements

In primates, activity in the visual cortex is not driven by spontaneous body movements. These results confirm the functional specialization of primate visual processing, in contrast with findings in mice, and highlight the importance of cross-species comparisons.

Bharath Chandra Talluri
Incheol Kang
Hendrikje Nienborg
ResearchOpen Access12 Oct 2023
Nature Neuroscience

Volume: 26, P: 1953-1959
Activation of a C-type virus from the human carcinoma cell line HBT-3 by iododeoxyuridine and testosterone

WALTER D. HOLDER JUN.
W. GERRY ROBEY
GEORGE F. VANDE WOUDE
Research21 Jun 1974
Nature

Volume: 249, P: 759-762
Mapping inequalities in exclusive breastfeeding in low- and middle-income countries, 2000–2018

Bhattacharjee and Schaeffer et al. map exclusive breastfeeding (EBF) in 94 low- and middle-income countries (LMICs), finding increased EBF practice and reduced subnational variation across the majority of LMICs from 2000 to 2018. However, only six LMICs will meet WHO’s target of ≥70% EBF by 2030 nationally, and only three will achieve this in all districts.

Natalia V. Bhattacharjee
Lauren E. Schaeffer
Simon I. Hay
ResearchOpen Access03 Jun 2021
Nature Human Behaviour

Volume: 5, P: 1027-1045
Dewetting of monolayer water and isopropanol between MoS₂ nanosheets

Beibei Wang
Rajiv K. Kalia
Priya D. Vashishta
ResearchOpen Access12 Nov 2018
Scientific Reports

Volume: 8, P: 1-6
Reaction with Iodine of Polysaccharides dissolved in Strong Calcium Chloride Solution

BLANCHE D. E. GAILLARD
R. W. BAILEY
Research08 Oct 1966
Nature

Volume: 212, P: 202-203
Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo cells

N. D. Hopwood
J. B. Gurdon
Research13 Sept 1990
Nature

Volume: 347, P: 197-200
Broadband observations of the naked-eye γ-ray burst GRB 080319B

Long duration γ-ray bursts (GRBs) release copious amounts of energy across the entire electromagnetic spectrum, and provide a window into the process of black hole formation from the collapse of massive stars. Observations of the extraordinarily bright prompt optical and γ-ray emission of GRB 080319B shows that the prompt emission stems from a single physical region, implying an extremely relativistic outflow that propagates within the narrow inner core of a two-component jet.

J. L. Racusin
S. V. Karpov
D. N. Burrows
Research11 Sept 2008
Nature

Volume: 455, P: 183-188
Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation

Codon 158 gain-of-function mutant p53 (158-mutp53) promotes tumourigenesis in lung cancer. Here, the authors show that 158-mutp53 render cancers sensitive to cisplatin and p53 acetylation agents through a mechanism where acetylated mutant p53 upregulates TRAIP and inhibits NF-ĸB signaling.

Li Ren Kong
Richard Weijie Ong
Boon Cher Goh
ResearchOpen Access29 Apr 2020
Nature Communications

Volume: 11, P: 1-17
Pig-to-human heart xenotransplantation in two recently deceased human recipients

In a short-term study in which hearts from gene-edited pigs were transplanted into two recently deceased human recipients, the hearts were able to function for the duration of the study without signs of rejection and without evidence of pig virus transmission, encouraging further clinical study of cardiac xenotransplantation.

Nader Moazami
Jeffrey M. Stern
Robert A. Montgomery
Research24 Jul 2023
Nature Medicine

Volume: 29, P: 1989-1997
High levels of cadmium in Atlantic seabirds and sea-skaters

K. R. BULL
R. K. MURTON
LANA CHENG
Research01 Oct 1977
Nature

Volume: 269, P: 507-509
Petroleum generation by laboratory-scale pyrolysis over six years simulating conditions in a subsiding basin

J. D. Saxby
K. W. Riley
Research08 Mar 1984
Nature

Volume: 308, P: 177-179
Inherited α-Lactalbumin and β-Lactoglobulin Polymorphism in Indian Zebu Cattle. Comparison of Zebu and Buffalo α-Lactalbumins

S. D. BHATTACHARYA
A. K. ROYCHOUDHURY
A. SEN
Research23 Feb 1963
Nature

Volume: 197, P: 797-799
A massive, cooling-flow-induced starburst in the core of a luminous cluster of galaxies

X-ray, optical and infrared observations reveal a very high rate of star formation in the core of an extremely luminous galaxy cluster; this starburst seems to be triggered by a cooling flow of the dense intracluster plasma.

M. McDonald
M. Bayliss
A. Zenteno
Research15 Aug 2012
Nature

Volume: 488, P: 349-352
Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS

Jun-Wei Liu
Dhyan Chandra
Dean G Tang
Research24 Jan 2005
Oncogene

Volume: 24, P: 2020-2031
Spontaneous excision of a large composite transposable element of Drosophila melanogaster

W. Chia
S. McGill
M. Ashburner
Research04 Jul 1985
Nature

Volume: 316, P: 81-83
Bright radio emission from an ultraluminous stellar-mass microquasar in M 31

A new ultraluminous X-ray source has been discovered in M 31, whose variability and associated bright, compact radio emission identify it as a stellar-mass black hole accreting close to the Eddington limit.

Matthew J. Middleton
James C. A. Miller-Jones
Keith Grainge
Research12 Dec 2012
Nature

Volume: 493, P: 187-190
Direct observation of the dead-cone effect in quantum chromodynamics

The direct measurement of the QCD dead cone in charm quark fragmentation is reported, using iterative declustering of jets tagged with a fully reconstructed charmed hadron.

S. Acharya
D. Adamova
N. Zurlo
ResearchOpen Access18 May 2022
Nature

Volume: 605, P: 440-446
Basal Hot Spot on a Surge Type Glacier

D. F. CLASSEN
G. K. C. CLARKE
Research12 Feb 1971
Nature

Volume: 229, P: 481-483
The ultraluminous interacting galaxy NGC6240

G. S. Wright
R. D. Joseph
W. P. S. Meikle
Research31 May 1984
Nature

Volume: 309, P: 430-431
Hidden order in URu₂Si₂ originates from Fermi surface gapping induced by dynamic symmetry breaking

What drives a phase transition in the heavy-fermion compound URu₂Si₂ is one of the major unsolved problems in condensed-matter physics. Numerical calculations now demonstrate how antiferromagnetic ordering leads to a symmetry breaking that alters the material’s band structure and therefore its electronic properties.

S. Elgazzar
J. Rusz
J. A. Mydosh
Research22 Feb 2009
Nature Materials

Volume: 8, P: 337-341
Accurate modeling and simulation of the effect of bacterial growth on the pH of culture media using artificial intelligence approaches

Suleiman Ibrahim Mohammad
Hamza Abu Owida
Ahmad Abumalek
ResearchOpen Access20 Aug 2025
Scientific Reports

Volume: 15, P: 1-19
Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer

A phase I clinical trial of an adjuvant personalized mRNA neoantigen vaccine, autogene cevumeran, in patients with pancreatic ductal carcinoma demonstrates that the vaccine can induce T cell activity that may correlate with delayed recurrence of disease.

Luis A. Rojas
Zachary Sethna
Vinod P. Balachandran
ResearchOpen Access10 May 2023
Nature

Volume: 618, P: 144-150
Measurement of anti-³He nuclei absorption in matter and impact on their propagation in the Galaxy

Measurements of the inelastic cross section of anti-³He allow the estimation of the transparency of the Milky Way to the propagation of these light antinuclei produced in either cosmic-ray collisions or annihilation of dark-matter particles.

S. Acharya
D. Adamová
N. Zurlo
ResearchOpen Access12 Dec 2022
Nature Physics

Volume: 19, P: 61-71
Ultraviolet luminosity density of the universe during the epoch of reionization

The luminosity of ultraviolet light emitted by the first galaxies in the universe traces the formation and evolution of stars and galaxies which led to the epoch of reionization. Here the authors use data from the Hubble Space Telescope and through a model provide a bound for the total luminosity.

Ketron Mitchell-Wynne
Asantha Cooray
Joseph Smidt
ResearchOpen Access08 Sept 2015
Nature Communications

Volume: 6, P: 1-13
Proper-motion age dating of the progeny of Nova Scorpii AD 1437

The re-discovery of the binary star system that created the Nova Scorpii AD 1437 stellar outburst shows that it is now a dwarf nova, suggesting that nova systems spend some time as dwarf novae in between larger outbursts.

M. M. Shara
K. Iłkiewicz
D. Zurek
Research31 Aug 2017
Nature

Volume: 548, P: 558-560
Newly formed dust within the circumstellar environment of SN Ia-CSM 2018evt

By day 1,041 after explosion, SN Ia-CSM 2018evt had produced an estimated 0.01 solar masses of dust in the cold, dense shell behind the supernova ejecta–circumstellar medium interaction, ranking it as one of the most prolific dust-producing supernovae ever recorded.

Lingzhi 灵芝 Wang王
Maokai Hu
Xinghan Zhang
ResearchOpen Access09 Feb 2024
Nature Astronomy

Volume: 8, P: 504-519
Comprehensive molecular characterization of urothelial bladder carcinoma

This paper reports integrative molecular analyses of urothelial bladder carcinoma at the DNA, RNA, and protein levels performed as part of The Cancer Genome Atlas project; recurrent mutations were found in 32 genes, including those involved in cell-cycle regulation, chromatin regulation and kinase signalling pathways; chromatin regulatory genes were more frequently mutated in urothelial carcinoma than in any other common cancer studied so far.

John N. Weinstein
Rehan Akbani
Greg Eley
ResearchOpen Access29 Jan 2014
Nature

Volume: 507, P: 315-322
Tailored semiconducting carbon nanotube networks with enhanced thermoelectric properties

Organic thermoelectric materials are emerging as low-cost, versatile alternatives to more established inorganic ones. Avery et al. report carbon nanotube-based materials with selected properties that exhibit enhanced thermoelectric performance.

Azure D. Avery
Ben H. Zhou
Andrew J. Ferguson
Research04 Apr 2016
Nature Energy

Volume: 1, P: 1-9
Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes

Longitudinal genomic and transcriptomic profiling of 1,143 patients with multiple myeloma by the Relating Clinical Outcomes in Multiple Myeloma to Personal Assessment of Genetic Profile study yields an improved copy number and gene expression subtype scheme, most notably a high-risk proliferative subtype associated with complete loss of RB1 or MAX.

Sheri Skerget
Daniel Penaherrera
Jonathan J. Keats
ResearchOpen Access19 Aug 2024
Nature Genetics

Volume: 56, P: 1878-1889
A remnant planetary core in the hot-Neptune desert

Observations of TOI-849b reveal a radius smaller than Neptune’s but a large mass of about 40 Earth masses, indicating that the planet is the remnant core of a gas giant.

David J. Armstrong
Théo A. Lopez
Zhuchang Zhan
Research01 Jul 2020
Nature

Volume: 583, P: 39-42
Reconciliation of energy use disparities in brick production in India

Energy efficient brick production is crucial for the carbon footprint, especially in countries with a continuously expanding built environment. This study models Indian brick production and reveals a large underreporting in official energy consumption estimates, as well as key drivers affecting its performance.

Kushal Tibrewal
Chandra Venkataraman
Baerbel Sinha
ResearchOpen Access29 Jun 2023
Nature Sustainability

Volume: 6, P: 1248-1257
Expression of human hprt gene on the inactive X chromosome after DNA-mediated gene transfer

A.J.R. de Jonge
P. J. Abrahams
D. Bootsma
Research18 Feb 1982
Nature

Volume: 295, P: 624-626
Author Correction: Genomic basis for RNA alterations in cancer

Claudia Calabrese
Natalie R. Davidson
Christian von Mering
Amendments and CorrectionsOpen Access25 Jan 2023
Nature

Volume: 614, P: E37
Weyl spin-momentum locking in a chiral topological semimetal

Spin-momentum locking is a fundamental property of condensed matter systems. Here, the authors evidence parallel Weyl spin-momentum locking of multifold fermions in the chiral topological semimetal PtGa.

Jonas A. Krieger
Samuel Stolz
Niels B. M. Schröter
ResearchOpen Access02 May 2024
Nature Communications

Volume: 15, P: 1-9
An anti-glitch in a magnetar

Magnetars sometimes exhibit mysterious ‘glitches’, during which angular momentum is transferred between the star’s outer and inner crusts, and involving a sudden spin-up of the star; here X-ray timing observations reveal a sudden spin-down, or ‘anti-glitch’ in a magnetar.

R. F. Archibald
V. M. Kaspi
J. A. Kennea
Research29 May 2013
Nature

Volume: 497, P: 591-593
The peripatetic fossils: part 3

The articles printed below are by co-authors of some of the papers called into doubt by Talent. Two are by close colleagues of Gupta at the Centre of Advanced Study in Geology at Panjab University.

A. D. Ahluwalia
Comments & Opinion07 Sept 1989
Nature

Volume: 341, P: 13-15

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