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Showing 351–400 of 427 results

Advanced filters: Author: D J Weatherall Clear advanced filters

Normal tissue radioprotection by amifostine via Warburg-type effects

Michael I. Koukourakis
Alexandra Giatromanolaki
Adrian L. Harris
ResearchOpen Access10 Aug 2016
Scientific Reports

Volume: 6, P: 1-14
Epidemiology and treatment of pulmonary arterial hypertension

The epidemiology of pulmonary arterial hypertension (PAH) has evolved considerably in the past 2 decades. In this Review, Lau and colleagues describe how this evolving epidemiology has influenced the treatment and management of PAH.

Edmund M. T. Lau
Eleni Giannoulatou
Marc Humbert
Reviews08 Jun 2017
Nature Reviews Cardiology

Volume: 14, P: 603-614
Checkpoint-blocker-induced autoimmunity is associated with favourable outcome in metastatic melanoma and distinct T-cell expression profiles

Weiyu Ye
Anna Olsson-Brown
Benjamin P. Fairfax
ResearchOpen Access15 Mar 2021
British Journal of Cancer

Volume: 124, P: 1661-1669
Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density

Steinkühler et al. use giant plasma membrane vesicles as a model system to study how plasma membranes respond to environmental changes, employing fluctuation spectroscopy and fluorescent probes. They show that the bending rigidity of plasma membranes vary with lipid order and microviscosity in correlated manner.

Jan Steinkühler
Erdinc Sezgin
Rumiana Dimova
ResearchOpen Access13 Sept 2019
Communications Biology

Volume: 2, P: 1-8
pH-susceptibility of HLA-DO tunes DO/DM ratios to regulate HLA-DM catalytic activity

Wei Jiang
Michael J. Strohman
Elizabeth D. Mellins
ResearchOpen Access27 Nov 2015
Scientific Reports

Volume: 5, P: 1-13
Characterising ¹⁸F-fluciclovine uptake in breast cancer through the use of dynamic PET/CT imaging

N. P. Scott
E. J. Teoh
D. R. McGowan
ResearchOpen Access18 Nov 2021
British Journal of Cancer

Volume: 126, P: 598-605
In silico guided reconstruction and analysis of ICAM-1-binding var genes from Plasmodium falciparum

Eilidh Carrington
Thomas D. Otto
Alister G. Craig
ResearchOpen Access19 Feb 2018
Scientific Reports

Volume: 8, P: 1-15
Continuous Indexing of Fibrosis (CIF): improving the assessment and classification of MPN patients

Hosuk Ryou
Korsuk Sirinukunwattana
Daniel Royston
ResearchOpen Access05 Dec 2022
Leukemia

Volume: 37, P: 348-358
Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma

T. P. MacGregor
R. Carter
R. A. Sharma
ResearchOpen Access08 May 2018
Scientific Reports

Volume: 8, P: 1-9
Characteristics of Susac syndrome: a review of all reported cases

Susac syndrome is an important differential diagnosis in many neurological disorders, but our understanding of this rare disease has largely been limited to reports of single cases and small case series. In this article, Dörr and colleagues review all reported cases of Susac syndrome to provide a comprehensive overview of demographic, clinical and diagnostic data on this disorder. On the basis of their findings, Dörr et al. make recommendations for diagnosis and management of individuals with suspected Susac syndrome.

Jan Dörr
Sarah Krautwald
Ilka Kleffner
Reviews30 Apr 2013
Nature Reviews Neurology

Volume: 9, P: 307-316
MHC class II proteins and disease: a structural perspective

MHC class II molecules are important factors that contribute to the susceptibility of an individual to autoimmune disease. Jones and colleagues look for clues to their involvement in disease by analysing crystal structures of peptide–MHC-class II complexes.

E. Yvonne Jones
Lars Fugger
Christian Siebold
Reviews01 Apr 2006
Nature Reviews Immunology

Volume: 6, P: 271-282
Synergistic activation of pro-inflammatory type-2 CD8⁺ T lymphocytes by lipid mediators in severe eosinophilic asthma

Bart Hilvering
Timothy S. C. Hinks
Luzheng Xue
ResearchOpen Access15 Jun 2018
Mucosal Immunology

Volume: 11, P: 1408-1419
Short and long-read genome sequencing methodologies for somatic variant detection; genomic analysis of a patient with diffuse large B-cell lymphoma

Hannah E. Roberts
Maria Lopopolo
David Buck
ResearchOpen Access19 Mar 2021
Scientific Reports

Volume: 11, P: 1-15
Genetic variability in response to infection: malaria and after

D J Weatherall
J B Clegg
Reviews03 Sept 2002
Genes & Immunity

Volume: 3, P: 331-337
Autoimmune synaptopathies

Autoantibodies against neuromuscular junction targets are a well-established cause of myasthenic syndromes, and autoantibodies against CNS targets have also been associated with disease. In this Review, Vincent and colleagues discuss key examples of such autoantibodies, and the mechanisms by which they lead to neurological dysfunction.

Sarah J. Crisp
Dimitri M. Kullmann
Angela Vincent
Reviews25 Jan 2016
Nature Reviews Neuroscience

Volume: 17, P: 103-117
High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage

J M Brenchley
K S Knox
D C Douek
Research11 Dec 2007
Mucosal Immunology

Volume: 1, P: 49-58
Hypoxia — a key regulatory factor in tumour growth

Adrian L. Harris
Reviews01 Jan 2002
Nature Reviews Cancer

Volume: 2, P: 38-47
Solving patients with rare diseases through programmatic reanalysis of genome-phenome data

Leslie Matalonga
Carles Hernández-Ferrer
Andreas Rump
ResearchOpen Access01 Jun 2021
European Journal of Human Genetics

Volume: 29, P: 1337-1347
RecQ helicases: caretakers of the genome

Ian D. Hickson
Reviews01 Mar 2003
Nature Reviews Cancer

Volume: 3, P: 169-178
WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel

Mara Artibani
Andrew H. Sims
Peter Hohenstein
ResearchOpen Access27 Mar 2017
Scientific Reports

Volume: 7, P: 1-15
A novel neurodegenerative spectrum disorder in patients with MLKL deficiency

Soren L. Faergeman
Hayley Evans
Lars Fugger
ResearchOpen Access01 May 2020
Cell Death & Disease

Volume: 11, P: 1-13
Author Correction: Normal tissue radioprotection by amifostine via Warburg-type effects

Michael I. Koukourakis
Alexandra Giatromanolaki
Adrian L. Harris
Amendments and CorrectionsOpen Access03 Feb 2025
Scientific Reports

Volume: 15, P: 1-4
A post-assembly genome-improvement toolkit (PAGIT) to obtain annotated genomes from contigs

Martin T Swain
Isheng J Tsai
Thomas D Otto
Protocols07 Jun 2012
Nature Protocols

Volume: 7, P: 1260-1284
The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays

Rachel Tanner
Matthew K. O’Shea
Helen McShane
ResearchOpen Access03 Mar 2017
Scientific Reports

Volume: 7, P: 1-13
Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141⁺XCR1⁺ dendritic cells

K M Silk
J D Silk
P J Fairchild
ResearchOpen Access10 Nov 2011
Gene Therapy

Volume: 19, P: 1035-1040
Phase I trial of intravesical Suramin in recurrent superficial transitional cell bladder carcinoma

J J Ord
E Streeter
A L Harris
ResearchOpen Access31 May 2005
British Journal of Cancer

Volume: 92, P: 2140-2147
GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia

A Maroz
L Stachorski
J-H Klusmann
Research13 Dec 2013
Leukemia

Volume: 28, P: 1259-1270
Increased error-prone non homologous DNA end-joining – a proposed mechanism of chromosomal instability in Bloom's syndrome

Terry J Gaymes
Phillip S North
Feyruz V Rassool
Research18 Apr 2002
Oncogene

Volume: 21, P: 2525-2533
Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway

K Ameri
E M Hammond
A L Harris
Research17 Jul 2006
Oncogene

Volume: 26, P: 284-289
HUWE1 variants cause dominant X-linked intellectual disability: a clinical study of 21 patients

Stéphanie Moortgat
Siren Berland
Ruth A. Newbury-Ecob
ResearchOpen Access27 Nov 2017
European Journal of Human Genetics

Volume: 26, P: 64-74
IE63-specific T-cell responses associate with control of subclinical varicella zoster virus reactivation in individuals with malignancies

G N Malavige
L T Rohanachandra
G S Ogg
ResearchOpen Access19 Jan 2010
British Journal of Cancer

Volume: 102, P: 727-730
Tissue and plasma expression of the angiogenic peptide adrenomedullin in breast cancer

M K Oehler
D C Fischer
R Bicknell
ResearchOpen Access11 Nov 2003
British Journal of Cancer

Volume: 89, P: 1927-1933
Changes of bone turnover markers and serum PTH after night or morning administration of zoledronic acid in breast cancer patients with bone metastases

D Generali
A Dovio
A Berruti
ResearchOpen Access27 May 2008
British Journal of Cancer

Volume: 98, P: 1753-1758
Congenital myasthenic syndrome with mild intellectual disability caused by a recurrent SLC25A1 variant

Sunitha Balaraju
Ana Töpf
Hanns Lochmüller
ResearchOpen Access16 Sept 2019
European Journal of Human Genetics

Volume: 28, P: 373-377
The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase

Qin Yang
Ran Zhang
Curtis C Harris
Research05 Apr 2004
Oncogene

Volume: 23, P: 3749-3756
Exome reanalysis and proteomic profiling identified TRIP4 as a novel cause of cerebellar hypoplasia and spinal muscular atrophy (PCH1)

Ana Töpf
Angela Pyle
Rita Horvath
ResearchOpen Access01 Jun 2021
European Journal of Human Genetics

Volume: 29, P: 1348-1353
NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease

T Schwerd
R V Bryant
H H Uhlig
ResearchOpen Access01 Nov 2017
Mucosal Immunology

Volume: 11, P: 562-574
Partial duplications of the ATRX gene cause the ATR-X syndrome

Bernard Thienpont
Thomy de Ravel
Koen Devriendt
Research20 Jun 2007
European Journal of Human Genetics

Volume: 15, P: 1094-1097
Increased pathological complete response rate after a long-term neoadjuvant letrozole treatment in postmenopausal oestrogen and/or progesterone receptor-positive breast cancer

G Allevi
C Strina
D Generali
ResearchOpen Access11 Apr 2013
British Journal of Cancer

Volume: 108, P: 1587-1592
Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide

Onima Chowdhury
Jennifer O’Sullivan
James Vardiman
Research07 Aug 2020
Leukemia

Volume: 35, P: 1197-1202
Role of lymphangiogenesis in epithelial ovarian cancer

S S Sundar
H Zhang
T S Ganesan
ResearchOpen Access09 May 2006
British Journal of Cancer

Volume: 94, P: 1650-1657
PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer

S-J Fan
C Snell
D C I Goberdhan
ResearchOpen Access05 Oct 2015
Oncogene

Volume: 35, P: 3004-3015
First international consensus on the methodology of lymphangiogenesis quantification in solid human tumours

I Van der Auwera
Y Cao
P B Vermeulen
ReviewsOpen Access21 Nov 2006
British Journal of Cancer

Volume: 95, P: 1611-1625
Parietal foramina with cleidocranial dysplasia is caused by mutation in MSX2

Sixto Garcia-Miñaur
Lampros A Mavrogiannis
Andrew O M Wilkie
Research22 Oct 2003
European Journal of Human Genetics

Volume: 11, P: 892-895
Promises and challenges of adoptive T-cell therapies for solid tumours

Matteo Morotti
Ashwag Albukhari
Ahmed A. Ahmed
ReviewsOpen Access29 Mar 2021
British Journal of Cancer

Volume: 124, P: 1759-1776
Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer

C Blick
A Ramachandran
A L Harris
ResearchOpen Access18 Jun 2013
British Journal of Cancer

Volume: 109, P: 50-59
Igf2 ligand dependency of Pten^+/− developmental and tumour phenotypes in the mouse

D N Church
B R Phillips
A B Hassan
ResearchOpen Access28 Nov 2011
Oncogene

Volume: 31, P: 3635-3646
Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells

E Bonhoure
A Lauret
O Cuvillier
Research10 Apr 2008
Leukemia

Volume: 22, P: 971-979
Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis

D C Singleton
P Rouhi
A L Harris
Research08 Dec 2014
Oncogene

Volume: 34, P: 4713-4722
Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

H Choudhry
A Albukhari
D R Mole
ResearchOpen Access24 Nov 2014
Oncogene

Volume: 34, P: 4482-4490

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