The formation and maturation of the neuromuscular junction require the concerted efforts of the presynaptic nerve terminal, the postsynaptic muscle fibre and perisynaptic Schwann cells. In this Review, Robitaille and colleagues describe the molecular and activity-dependent processes that underlie the development of neuron–muscle contacts.
- Houssam Darabid
- Anna P. Perez-Gonzalez
- Richard Robitaille
