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Showing 101–150 of 160 results

Advanced filters: Author: D Mahon Clear advanced filters

Genome-wide significant association between a ‘negative mood delusions’ dimension in bipolar disorder and genetic variation on chromosome 3q26.1

S Meier
M Mattheisen
M Rietschel
ResearchOpen Access25 Sept 2012
Translational Psychiatry

Volume: 2, P: e165
Bcr-abl translocation can occur during the induction of multidrug resistance and confers apoptosis resistance on myeloid leukemic cell lines

Francis Belloc
Sophie Cotteret
Francis Lacombe
Research01 Dec 1997
Cell Death & Differentiation

Volume: 4, P: 806-814
Retromer in Alzheimer disease, Parkinson disease and other neurological disorders

Retromer is a protein assembly that has a crucial role in endosomal sorting and trafficking. In this Progress article, Small and Petsko discuss the role of retromer dysfunction in various neurological diseases, including Alzheimer disease and Parkinson disease.

Scott A. Small
Gregory A. Petsko
Reviews11 Feb 2015
Nature Reviews Neuroscience

Volume: 16, P: 126-132
A phase 2 study of MK-0457 in patients with BCR-ABL T315I mutant chronic myelogenous leukemia and philadelphia chromosome-positive acute lymphoblastic leukemia

J F Seymour
D W Kim
F J Giles
ResearchOpen Access15 Aug 2014
Blood Cancer Journal

Volume: 4, P: e238
Does long-term culture favor normal clonogenic cells from interferon-treated patients with chronic myelogenous leukemia?

G Pasternak
B Schultheis
R Hehlmann
Reviews15 Jun 1999
Leukemia

Volume: 13, P: S55-S64
Therapy of chronic myeloid leukaemia can benefit from the activation of stem cells: simulation studies of different treatment combinations

I Glauche
K Horn
I Roeder
ResearchOpen Access26 Apr 2012
British Journal of Cancer

Volume: 106, P: 1742-1752
Onconeuronal cerebellar degeneration-related antigen, Cdr2, is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response

K Balamurugan
V-D Luu
G Camenisch
Research06 Jul 2009
Oncogene

Volume: 28, P: 3274-3285
Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-γ1-driven activation of mTOR/p70S6-kinase pathway

B Markova
C Albers
T Fischer
Research02 Nov 2009
Oncogene

Volume: 29, P: 739-751
Characterization of a reference material for BCR-ABL (M-BCR) mRNA quantitation by real-time amplification assays: towards new standards for gene expression measurements

J Saldanha
M Silvy
J Gabert
Research03 May 2007
Leukemia

Volume: 21, P: 1481-1487
Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype

K Ameri
R Luong
S S Jeffrey
ResearchOpen Access05 Jan 2010
British Journal of Cancer

Volume: 102, P: 561-569
AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL

E Weisberg
P Manley
J D Griffin
ReviewsOpen Access23 May 2006
British Journal of Cancer

Volume: 94, P: 1765-1769
Nilotinib is effective in imatinib-resistant or -intolerant patients with chronic myeloid leukemia in blastic phase

F J Giles
H M Kantarjian
O G Ottmann
Research13 Dec 2011
Leukemia

Volume: 26, P: 959-962
Long-term treatment-free remission in patients with chronic myeloid leukemia after second-line nilotinib: ENESTop 5-year update

Timothy P. Hughes
Nelma Cristina D. Clementino
Francois-Xavier Mahon
Research12 May 2021
Leukemia

Volume: 35, P: 1631-1642
Evaluation of the effects of fixed combinations of sustained-release verapamil/trandolapril versus captopril/hydrochlorothiazide on metabolic and electrolyte parameters in patients with essential hypertension

R Cifková
R Nakov
D Compagnone
Research21 Jun 2000
Journal of Human Hypertension

Volume: 14, P: 347-354
Mutation status and clinical outcome of 89 imatinib mesylate-resistant chronic myelogenous leukemia patients: a retrospective analysis from the French intergroup of CML (Fi(ϕ)-LMC GROUP)

F E Nicolini
S Corm
C Roche-Lestienne
Research27 Apr 2006
Leukemia

Volume: 20, P: 1061-1066
White Matter Abnormalities in Pediatric Obsessive-Compulsive Disorder

Patricia Gruner
An Vo
Philip R Szeszko
Research08 Aug 2012
Neuropsychopharmacology

Volume: 37, P: 2730-2739
Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo

S A Bright
A M McElligott
D M Zisterer
ResearchOpen Access20 Apr 2010
British Journal of Cancer

Volume: 102, P: 1474-1482
The influence of hypoxia on CML trafficking through modulation of CXCR4 and E-cadherin expression

A K Azab
E Weisberg
I M Ghobrial
Correspondence05 Dec 2012
Leukemia

Volume: 27, P: 961-964
Parental perceptions of feeding practices in five European countries: an exploratory study

K Synnott
J Bogue
R Adam
Research17 Jan 2007
European Journal of Clinical Nutrition

Volume: 61, P: 946-956
PHD2 in tumour angiogenesis

D A Chan
A J Giaccia
ReviewsOpen Access11 May 2010
British Journal of Cancer

Volume: 103, P: 1-5
MDR1 expression predicts outcome of Ph+ chronic phase CML patients on second-line nilotinib therapy after imatinib failure

M Agrawal
B Hanfstein
M C Müller
Research10 Jan 2014
Leukemia

Volume: 28, P: 1478-1485
Analysis of chronic myeloid leukaemia during deep molecular response by genomic PCR: a traffic light stratification model with impact on treatment-free remission

Katerina Machova Polakova
Hana Zizkova
Andreas Hochhaus
Research29 May 2020
Leukemia

Volume: 34, P: 2113-2124
Serum urate and cardiovascular events in the DCCT/EDIC study

Alicia J. Jenkins
Barbara H. Braffett
T. Woodfill
ResearchOpen Access09 Jul 2021
Scientific Reports

Volume: 11, P: 1-11
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Till F. M. Andlauer
Jose Guzman-Parra
Marcella Rietschel
ResearchOpen Access11 Nov 2019
Molecular Psychiatry

Volume: 26, P: 1286-1298
A Voxel-Based Diffusion Tensor Imaging Study of White Matter in Bipolar Disorder

Katie Mahon
Jinghui Wu
Philip R Szeszko
Research14 Jan 2009
Neuropsychopharmacology

Volume: 34, P: 1590-1600
Molecular genetics of familial hypertrophic cardiomyopathy (FHC)

M. D. Bashyam
G. R. Savithri
P. Nallari
Reviews01 Feb 2003
Journal of Human Genetics

Volume: 48, P: 55-64
SIRT7: an influence factor in healthy aging and the development of age-dependent myeloid stem-cell disorders

Alexander Kaiser
Martin Schmidt
Thomas Ernst
ResearchOpen Access25 Mar 2020
Leukemia

Volume: 34, P: 2206-2216
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

Simone de Jong et al. examine the balance of common and rare risk for psychiatric disorders in a large family with high incidence of Bipolar Disorder and Major Depressive Disorder. They find that increased polygenic risk over generations could be partially due to assortative mating, which may explain the observation of anticipation in mood disorders.

Simone de Jong
Mateus Jose Abdalla Diniz
Gerome Breen
ResearchOpen Access08 Oct 2018
Communications Biology

Volume: 1, P: 1-10
2025 European LeukemiaNet recommendations for the management of chronic myeloid leukemia

Jane F. Apperley
Dragana Milojkovic
Rüdiger Hehlmann
ReviewsOpen Access11 Jul 2025
Leukemia

Volume: 39, P: 1797-1813
An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations

C. Stayner
C. A. Poole
M. R. Eccles
ResearchOpen Access09 May 2017
Scientific Reports

Volume: 7, P: 1-15
The importance of prediction model validation and assessment in obesity and nutrition research

A E Ivanescu
P Li
D B Allison
Reviews09 Oct 2015
International Journal of Obesity

Volume: 40, P: 887-894
The value of the continuous genotyping of multi-drug resistant tuberculosis over 20 years in Spain

María José Iglesias
Daniel Ibarz
M. I. Galán
ResearchOpen Access24 Nov 2020
Scientific Reports

Volume: 10, P: 1-12
A genome-wide association study of attempted suicide

V L Willour
F Seifuddin
J B Potash
Research22 Mar 2011
Molecular Psychiatry

Volume: 17, P: 433-444
Chromosome orientation fluorescence in situ hybridization to study sister chromatid segregation in vivo

Ester Falconer
Elizabeth Chavez
Peter M Lansdorp
Protocols01 Jul 2010
Nature Protocols

Volume: 5, P: 1362-1377
The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis

B G Mar
D Amakye
S Buonamici
Reviews10 Jun 2011
Leukemia

Volume: 25, P: 1665-1673
Methylated Glutathione S-transferase 1 (mGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer

K L Mahon
W Qu
S J Clark
ResearchOpen Access21 Aug 2014
British Journal of Cancer

Volume: 111, P: 1802-1809
Enabling recruitment success in bariatric surgical trials: pilot phase of the By-Band-Sleeve study

S Paramasivan
C A Rogers
J L Donovan
ResearchOpen Access03 Jul 2017
International Journal of Obesity

Volume: 41, P: 1654-1661
Cancer treatment with kinase inhibitors: what have we learnt from imatinib?

D M Ross
T P Hughes
ReviewsOpen Access06 Jan 2004
British Journal of Cancer

Volume: 90, P: 12-19
Development and evaluation of a secondary reference panel for BCR-ABL1 quantification on the International Scale

N C P Cross
H E White
S Branford
ResearchOpen Access25 Apr 2016
Leukemia

Volume: 30, P: 1844-1852
GILZ inhibits the mTORC2/AKT pathway in BCR-ABL⁺ cells

S Joha
A-L Nugues
T Idziorek
ResearchOpen Access01 Aug 2011
Oncogene

Volume: 31, P: 1419-1430
PI3K/mTOR pathway inhibitors sensitize chronic myeloid leukemia stem cells to nilotinib and restore the response of progenitors to nilotinib in the presence of stem cell factor

K Airiau
F-X Mahon
F Belloc
ResearchOpen Access03 Oct 2013
Cell Death & Disease

Volume: 4, P: e827
JAK the trigger

François-Xavier Mahon
Comments & Opinion04 Jul 2005
Oncogene

Volume: 24, P: 7125-7126
Frontline nilotinib in patients with chronic myeloid leukemia in chronic phase: results from the European ENEST1st study

A Hochhaus
G Rosti
F J Giles
ResearchOpen Access06 Oct 2015
Leukemia

Volume: 30, P: 57-64
Cytokine profiling of docetaxel-resistant castration-resistant prostate cancer

K L Mahon
H-M Lin
L G Horvath
ResearchOpen Access31 Mar 2015
British Journal of Cancer

Volume: 112, P: 1340-1348
Effect of tyrosine kinase inhibitors on stemness in normal and chronic myeloid leukemia cells

L Charaf
F-X Mahon
A Bedel
Research25 May 2016
Leukemia

Volume: 31, P: 65-74
Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants

E R Gamazon
J A Badner
C Liu
Research03 Jan 2012
Molecular Psychiatry

Volume: 18, P: 340-346
Efficacy of dual-specific Bcr-Abl and Src-family kinase inhibitors in cells sensitive and resistant to imatinib mesylate

A J Tipping
S Baluch
J V Melo
News17 Jun 2004
Leukemia

Volume: 18, P: 1352-1356
Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results

T P Hughes
B Leber
J H Lipton
CorrespondenceOpen Access03 Aug 2017
Leukemia

Volume: 31, P: 2529-2531
Imatinib dose escalation for chronic phase–chronic myelogenous leukaemia patients in primary suboptimal response to imatinib 400 mg daily standard therapy

D Rea
G Etienne
F E Nicolini
Correspondence26 Feb 2009
Leukemia

Volume: 23, P: 1193-1196
Low incidence of peripheral arterial disease in patients receiving dasatinib in clinical trials

P D le Coutre
T P Hughes
J E Cortes
CorrespondenceOpen Access21 Dec 2015
Leukemia

Volume: 30, P: 1593-1596

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