Nature Search

Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability

Natural hair colour in Europeans is a complex genetic trait. Here, the authors carry out a genome-wide association study using UK BioBank data, suggesting that in combination with pigmentation genes, variants with roles in hair texture and growth can affect hair colouration or our perception of it.

Michael D. Morgan
Erola Pairo-Castineira
Ian J. Jackson
ResearchOpen Access10 Dec 2018
Nature Communications

Volume: 9, P: 1-10
Discovering genetic interactions bridging pathways in genome-wide association studies

Genetic interactions may contribute to phenotypic traits but are challenging to decipher. Here, the authors develop BridGE, a computational approach for identifying pathways connected by genetic interactions from GWAS data.

Gang Fang
Wen Wang
Chad L. Myers
ResearchOpen Access19 Sept 2019
Nature Communications

Volume: 10, P: 1-18
Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is a chronic allergic inflammatory disease with a complex underlying genetic etiology. Here, the authors identify a series of rare variants in DSP and PPL in multiplex families with EoE and uncover a pathogenic role for desmosomal dysfunction in EoE.

Tetsuo Shoda
Kenneth M. Kaufman
Marc E. Rothenberg
ResearchOpen Access23 Nov 2021
Nature Communications

Volume: 12, P: 1-15
Deep sequencing of candidate genes identified 14 variants associated with smoking abstinence in an ethnically diverse sample

Paul M. Cinciripini
David W. Wetter
Sanjay Shete
ResearchOpen Access16 Mar 2024
Scientific Reports

Volume: 14, P: 1-15
The heterogeneity in link weights may decrease the robustness of real-world complex weighted networks

M. Bellingeri
D. Bevacqua
D. Cassi
ResearchOpen Access23 Jul 2019
Scientific Reports

Volume: 9, P: 1-13
Metabolic and Genetic Studies of a Family with Ornithine Transcarbamylase Deficiency

Arnold S Goldstein
Nicholas J Hoogenraad
Philip Sunshine
Research01 Jan 1974
Pediatric Research

Volume: 8, P: 5-12
Genome-wide interaction and pathway-based identification of key regulators in multiple myeloma

Subhayan Chattopadhyay et al. conduct genome-wide interaction studies to identify genetic susceptibility to multiple myeloma. They find 16 unique interacting loci, which implicate immune response in multiple myeloma pathology.

Subhayan Chattopadhyay
Hauke Thomsen
Asta Försti
ResearchOpen Access04 Mar 2019
Communications Biology

Volume: 2, P: 1-10
Conditioning of Superconductive Properties in Graph-Shaped Reticles

M. Lucci
D. Cassi
M. Cirillo
ResearchOpen Access23 Jun 2020
Scientific Reports

Volume: 10, P: 1-8
AUTOANTIBODY MARKERS FOR INSULITIS IN THE FAMILIES OF INSULIN DEPENDENT DIABETICS

P Betts
T J Wilkin
D Lee
Research01 Nov 1986
Pediatric Research

Volume: 20, P: 1205
A comparative analysis of link removal strategies in real complex weighted networks

M. Bellingeri
D. Bevacqua
D. Cassi
ResearchOpen Access03 Mar 2020
Scientific Reports

Volume: 10, P: 1-15
A comparison of node vaccination strategies to halt SIR epidemic spreading in real-world complex networks

F. Sartori
M. Turchetto
D. Cassi
ResearchOpen Access09 Dec 2022
Scientific Reports

Volume: 12, P: 1-13
Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium

Constantinos Constantinides
Laura K. M. Han
Esther Walton
ResearchOpen Access09 Dec 2022
Molecular Psychiatry

Volume: 28, P: 1201-1209
COVID-19-related psychological distress and engagement in preventative behaviors among individuals with severe mental illnesses

Amy E. Pinkham
Robert A. Ackerman
Raeanne C. Moore
ResearchOpen Access03 Feb 2021
npj Schizophrenia

Volume: 7, P: 1-7

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