Lymphocytes crawl on blood vessels against the flow of blood, but the mechanism for this directed migration is not known. Here, Valignat et al.show that lymphocytes can use their uropods as wind vanes to passively steer their migration in the presence of fluid flow, without the need for internal guidance cues.
- Marie-Pierre Valignat
- Paulin Nègre
- Olivier Theodoly
