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Showing 1–5 of 5 results
Advanced filters: Author: D. Reisel Clear advanced filters

  • Most ovarian cancers originate from cells originally derived from Müllerian Duct cells. Here, the authors show that the methylation profile of Müllerian Duct cells isolated from cervical samples can predict whether a woman has cervical cancer.

    • James E. Barrett
    • Allison Jones
    • Martin Widschwendter
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12

  • Risk-adapted approaches to breast cancer prevention and screening could potentially be more effective than universal approaches, which have important limitations. In this Consensus Statement, representatives of the European Collaborative on Personalized Early Detection and Prevention of Breast Cancer (ENVISION) discuss the current state of breast cancer risk prediction, risk-stratified prevention and early detection strategies, and their implementation. They also present the ENVISION recommendations on priorities for future research in each of these areas with the aim of stimulating and guiding risk-adapted breast cancer prevention and screening programmes.

    • Nora Pashayan
    • Antonis C. Antoniou
    • Martin Widschwendter
    ReviewsOpen Access
    Nature Reviews Clinical Oncology
    Volume: 17, P: 687-705

  • The development of cancer involves several epigenomic alterations, and the presence of certain alterations before the development of cancer is associated with cancer risk. In this Review, the authors describe the potential of epigenomics-based assays to predict an individual's risk of cancer, including discussions of technical, practical and societal issues regarding the implementation of such assays.

    • Martin Widschwendter
    • Allison Jones
    • Nora Pashayan
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 15, P: 292-309