Utilizing a self-referenced detection scheme based on the mode-splitting in an ultrahigh-Q microresonator, scientists realize the real-time in situ detection and sizing of single nanoparticles with radii as small as 30 nm. Labelling of the particles and a priori information on the presence of nanoparticles in the medium are not required, thus providing an effective platform for studying nanoparticles at the single-particle resolution level.
- Jiangang Zhu
- Sahin Kaya Ozdemir
- Lan Yang